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Patient Care

Acoustic Neuroma – Cranial (Skull) Base Surgery

Clinical Services: Ear, Nose and Throat (ENT; Otolaryngology - Head and Neck Surgery)
Upper East Side
1305 York Avenue, 5th Floor
New York, NY 10021

NewYork-Presbyterian Hospital/Weill Cornell Medical Center has long been regarded as one of our nation's leading institutions in the care of the complicated patient. This tradition has continued in the field of cranial base surgery. Technological and surgical advances has made treatment of cranial base tumors a reality.

Multidisciplinary Approach

The foundation of successful treatment of the patient with a cranial base tumor is a multidisciplinary approach to their complex problems. The Consortium on Cranial Base Surgery is composed of neurosurgeons, neurotologists, head and neck surgeons, neurophysiologists, neuroanesthesiologists, neuroradiologists, plastic and reconstructive surgeons, and maxillofacial surgeons. Each of these subspecialsists bring their own specific expertise in the care of the patient with a cranial base lesion.

Definition & Growth Patterns

Acoustic neuromas, also known as vestibular schwannomas, are benign tumors that arise from the cochleovestibular (hearing and balance) nerve. Over 5,000 of these tumors are diagnosed in the United States per year. These tumors are slow growing and begin within the temporal bone which contains the inner ear. As these tumors expand, they grow into the intracranial cavity and lead to compression of cranial nerves that regulate facial movement, facial sensation, hearing, balance, speech and swallowing. In addition, the portion of the brain that regulates coordination and motion (the cerebellum) and the brainstem itself may be severely compressed by these tumors. Early in tumor growth, the acoustic neuroma is limited to the internal auditory canal. Patients with a stage one, or intracanalicular-stage, acoustic neuroma (confined entirely inside the internal auditory canal) often complain of difficulty with hearing in one ear, which may begin suddenly or insidiously. Hearing loss may be accompanied by noise inside the ear (tinnitus), dizziness and vertigo.

Intracanalicular Acoustic Neuroma

Intracanalicular Acoustic Neuroma

Figure 1 is a view of the head from above. The posterior fossa with the intracranial contents of the cerebellum, brain stem and cranial nerves, as well as the temporal bone can be seen. The temporal bone is a part of the skull base. In the temporal bone is the internal auditory canal that allows the cochleovestibular (hearing and balance) nerve and the facial nerve to pass from their intracranial site of origin to either the cochlea (snail-like hearing organ), vestibular apparatus (balance organ with three semicircular canals), or the muscles that move the face. Acoustic neuromas most commonly arise in this canal. In Figure 1, a small intracanalicular tumor (colored brown in this illustration) can be seen.

Acoustic Neuroma in the CPA

Acoustic Neuroma in the CPA

In Figure 2, a larger acoustic neuroma (colored brown) is present. This tumor has grown out of the internal auditory canal into the region known as the cerebellopontine angle, or CPA. The tumor has a characteristic shape, with a root-like extension in the internal auditory canal and a globular portion in the intracranial cavity, just touching the brainstem, cerebellum and parts of the cranial nerves. Patients may have the same symptoms as when a tumor is in the internal auditory canal or patients may have additional symptoms including headaches.


Brainstem Compression Stage

Brainstem Compressive Stage

The brainstem compressive stage can be seen in Figure 3. In this figure the brainstem, cerebellum and cranial nerves are being compressed by the tumor. Acoustic neuromas are almost universally benign (not cancer), so they do not erode into or replace brain tissue. Rather, acoustic neuromas cause damage by taking up space in the intracranial cavity where no extra space exists. Compression and attenuation of vital structures in this stage can lead to increased headaches and numbness of the face.


DefinitionFinal Stage of Acoustic Neuroma Growth

Final Stage of Acoustic Neuroma Growth

Drainage of the cerebrospinal fluid in the head that bathes the brain, increased pressure and further compression of the brainstem, cerebellum and cranial nerves result in severe symptoms, including difficulty producing speech, swallowing and breathing, double vision and eventually death. It is very unusual for patients to have tumors this large without seeking medical help when the tumors are in a smaller stage. Acoustic neuromas characteristically grow slowly, usually over years. Smaller tumors very rarely grow to the point seen in the figure above.

Treatment Options

The choice of which treatment is most appropriate for a patient is based on a number of factors including: tumor size, tumor location, tumor characteristics (cystic versus solid tumors), degree of hearing loss, presence of other symptoms, prior surgery, prior radiation, patient age and health, the presence of syndromic acoustic neuroma (Type 2 neurofibromatosis) and, ultimately, patient preference.

Serial observation, watching a tumor on MRI scans over time, is often the most appropriate form of treatment. However, primary radiosurgery or microsurgery are frequently necessary. If surgery is recommended, one of three primary surgical approaches will be used on the basis of the factors noted above.

Our skull base surgery team is composed of a neurologist, skull base surgeon and neurosurgeon who performs microsurgical lesion resection. During microsurgery, the region of the brain and electrophysiologic nerves compressed by the tumor are monitored.

We perform all three forms of therapy – watchful waiting, radiosurgery and microsurgery

Cranial Base Tumors

Cranial base tumors arise in, or impinge upon, the bony cranium. They may arise:

  • Beneath the cranial base and ascend to it, as in squamous cell carcinomas of the head and neck.
  • Within the bones of the cranial base, as in acoustic neuromas, glomus tumors, or temporal bone petrous apex cholesterol granulomas.
  • Above the cranial base, and extend interiorly to involve the cranial base through bony erosion, as in meningiomas, chordomas or sarcomas.

Surgical treatment approaches for cranial base tumor patients include anterior, middle and posterior fossa craniotomies, craniofacial resections, and craniotomies through the temporal bone (translabyrinthine, transcochlear and infratemporal fossa). Additionally, transcervical and transfacial routes are often employed.

Multichannel Intraoperative Neural Monitoring

Our Cranial Base Surgery Consortium utilizes sophisticated intraoperative neural monitoring technology to maximize postoperative cranial nerve function. Simultaneous four-channel cranial nerve monitoring is individually adapted to each specific surgery. Motor nerve monitoring through electromyography, as well as sensory monitoring of Auditory Brain Stem Evoked Responses (ABR) and Somatosensory Evoked Potentials (SSEP), are capabilities of this technology. Our physician neurophysiologists in the operating room during surgery also play an integral role in intraoperative patient care.

200-Year Tradition of Excellence

Although the field of cranial base surgery has only recently evolved, our medical center boasts a 200-year tradition of excellence in patient care, education and leadership. Weill Cornell Medicine patients continue to benefit from our institution’s high success rates, peerless education system and preeminent physicianship.

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