Transcranial Magnetic Stimulation (TMS) Program

Upper East Side
1165 York Avenue
New York, NY 10065

Personalized, Evidence-Based TMS for Depression, From the Team That Helped Develop the Science

Transcranial Magnetic Stimulation (TMS) is an FDA-cleared, non-invasive treatment for depression that hasn’t responded to medication. Our program was developed and is led by the clinician-scientists of the Precision Psychiatry Institute at Weill Cornell Medicine. We engage in groundbreaking research, develop new TMS protocols and other technologies and offer fMRI-guided, individualized treatment.

Get Started

Our clinical program is launching in early 2027. To learn more, contact our referral coordinator, Melanie Cabrera, at mec4002@med.cornell.edu.

What is TMS?

Transcranial magnetic stimulation uses focused magnetic pulses, like those used in MRI, to stimulate brain regions that regulate mood. In depression, activity in these regions is often reduced. A course of TMS is designed to restore healthier activity in this network, which can relieve depression in people for whom medications haven’t worked well enough.

TMS is non-invasive and doesn’t involve medication, anesthesia or sedation. You remain awake and seated in a chair while an electromagnetic coil device positioned against the scalp delivers brief pulses that feel like a light tapping. Most people resume their daily activities, including driving, immediately after a session.

TMS has been proven equal to another FDA-approved device used to treat major depressive disorder, and is supported by a large body of clinical research. It is an established treatment, not an experimental one.

What Distinguishes Our Program

Guided by the Scientists Who Built the Research

Our program was created and is guided by clinician-scientists of the Precision Psychiatry Institute at Weill Cornell Medicine, the same investigators whose research has helped define how depression is understood and treated with brain stimulation. Immanuel Elbau, M.D., Ph.D., leads the program, and scientific leadership is provided by Conor Liston, M.D., Ph.D., and Charles Lynch, Ph.D. Because our care is delivered by experts who helped develop this advanced treatment, we rely on current evidence rather than long-standing convention.

Ensuring Insurance Coverage

We provide TMS as an insurance-covered treatment, and our team helps you navigate your coverage. We work with most major commercial plans, Medicare and Medicaid, and we manage prior authorization so you don’t have to.

FMRI-Guided Targeting Through Our Research

Conventional TMS often positions the electromagnetic device (coil) based on the typical brain anatomy (fixed scalp measurement). Our research initiatives focus on fMRI, which can identify your specific brain-network targets and then individualize treatments using neuronavigation, a unique map of your brain anatomy. We offer fMRI treatments as part of clinical trials that don’t involve medications or placebos.

Conditions We Treat

At Weill Cornell Medicine, we may recommend TMS if you experience:

  • Major depressive disorder. This includes depression experienced by people who can’t tolerate antidepressant side effects or prefer to avoid medication.
  • Major depression with anxious features, depression experienced alongside ongoing worry or restlessness.
  • Obsessive-Compulsive Disorder (OCD). Repetitive, intrusive thoughts paired with compulsive behaviors. For OCD, we use a distinct FDA-cleared TMS protocol delivered with a specialized coil.
  • Treatment-resistant depression, major depression that hasn’t improved sufficiently after one or more medication trials.

TMS is covered by most insurance plans, including Medicare and Medicaid, for major depressive disorder, including treatment-resistant depression and depression with anxious features. TMS for OCD is FDA-cleared, but insurance coverage is less consistent, and our team will verify your specific benefits before treatment begins.

Unsure whether you qualify? Contact us to learn more.

Our Services

Weill Cornell Medicine offers TMS treatment for depression, and a newer accelerated protocol for patients who need a faster course.

  • TMS: we deliver TMS using intermittent Theta-Burst Stimulation (iTBS), an FDA-cleared protocol in which each session involves only about three minutes of stimulation. Treatment is typically five days per week for about six weeks, followed by a brief taper. This standard course is covered by insurance.
  • Accelerated intermittent Theta-Burst Stimulation (iTBS): with this condensed protocol, we deliver about ten treatments per day over five days. Our team has conducted some of the largest studies of this approach in collaboration with Stanford Medicine. As a newer protocol, accelerated iTBS isn’t currently covered by all insurance companies and is offered on a fee-for-service basis. Our team will review the protocol, expected outcomes and cost with you.

Your team will work with you to determine the appropriate protocol for you at your evaluation.

TMS: What to Expect

If you’re considering transcranial magnetic stimulation, here is what to expect from start to finish.

  1. Reach out to us. Contact us directly by emailing Melanie Cabrera at mec4002@med.cornell.edu.
  2. Evaluation: we contact you to arrange a no-cost evaluation with a psychiatrist to review your history and determine whether TMS is right for you.
  3. Insurance: we work with your insurance provider to verify your benefits and obtain prior authorization. Additionally, we confirm your coverage and any out-of-pocket costs before treatment begins.
  4. fMRI visit: if you receive fMRI-guided treatment through our research studies, you come in for a single, one-hour MRI visit. This simple, non-invasive brain scan requires no injection or radiation and shows how your individual brain networks are organized. Using your MRI, our team performs electric-field modeling and individualized brain-network mapping to define the precise location and dose for your treatment.
  5. Treatment: you begin your course of TMS, delivered as iTBS or the accelerated protocol, as decided with your psychiatrist. Sessions are delivered with brain-network mapping to your individualized target.
  6. Follow-up: we track your progress with standardized clinical measures and coordinate with your existing psychiatrist or therapist to support improvement over time.

What a Session Is Like

You sit in a chair, awake and alert. The device rests against your scalp and delivers pulses that feel like a gentle tapping. With iTBS, each session involves about three minutes of stimulation. You may read, listen to music or rest. Afterward, there’s no recovery period, and you may drive yourself home.

Side Effects

TMS rarely causes side effects. If side effects occur, they’re generally mild. The most common side effects include short-term scalp discomfort or a mild headache during the first week, which typically go away on their own.

Our TMS Team

Our care is provided by leaders in the field who have extensive experience in interventional psychiatry, neuromodulation and brain imaging.

  • Immanuel Elbau, M.D., Ph.D, Clinical Director, Weill Cornell Medicine Assistant Professor of Psychiatry, directs the clinical program and leads its fMRI-guided personalization of TMS. He is active in both patient care and research.
  • Conor Liston, M.D., Ph.D., Vice Chair of Precision Psychiatry, Weill Cornell Medicine Professor of Psychiatry, researches depression circuits, neuromodulation and the science underlying TMS.
  • Charles Lynch, Ph.D., Weill Cornell Medicine Assistant Professor of Neuroscience in Psychiatry, researches precision brain-network mapping and individualized targeting.

Insurance

TMS for treatment-resistant depression is covered by most major commercial insurance plans, Medicare and New York Medicaid. It is an established, FDA-cleared treatment, and our standard iTBS-based TMS is covered on this basis. Our team verifies your benefits and determines your coverage.

Your Coverage Is Independent of the FMRI

Insurance coverage for TMS is the same whether you receive traditional TMS or fMRI-guided targeting through one of our studies. Study participation is at no cost to you. The fMRI is provided through our research program and doesn’t affect insurance coverage.

What to Expect

Most plans require prior authorization before treatment begins. Before treatment begins, our team will verify benefits, assemble documentation, submit authorization, plan coverage and your out-of-pocket costs.

What Insurers Typically Require

Criteria vary by plan, but your insurance company may require a diagnosis of major depressive disorder, a history of ongoing depression despite at least two attempts at antidepressant medication, and, for some plans, documentation of a psychotherapy trial, along with standard clinical documentation from your evaluation. If you’re an ideal candidate for TMS, we will provide all of this information to your insurance company.

Note: Accelerated iTBS is a newer protocol and isn’t yet reliably covered by insurance; it is offered on a fee-for-service basis.

Our Research

Our research initiative focuses on advancing innovative methods in mental health treatment at the Precision Psychiatry Institute at Weill Cornell Medicine. We explore how brain networks affect mood and the mechanisms of brain stimulation therapies to provide more personalized care.

Currently, we have several studies open for enrollment, including clinical trials and observational research. Participation is voluntary and separate from clinical treatment, and eligibility is determined during a screening visit. Compensation is offered for participation.

Interested patients and referring providers can learn about current research studies and recent publications here.

Media Coverage

Contact Us About TMS

To see if you are eligible for our research and clinical trials open to enrollment, click here.

To learn more about our clinical program launching in early 2027, contact Melanie Cabrera at mec4002@med.cornell.edu. 

575 Lexington Avenue, Fourth Floor, New York, NY 10022

For Referring Providers

We make the referral process straightforward and manage each step on your behalf, from insurance coverage to clinical evaluations. As the referring provider, you continue to direct your patient's overall care.

Contact Melanie Cabrera, our referral coordinator, at mec4002@med.cornell.edu to refer or discuss a patient.

Social Media

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