Cytogenetics

The Cytogenetics laboratory at Weill Cornell Medical College/New York Presbyterian Hospital performs approximately 7500 tests annually, with the use of conventional cytogenetic and molecular cytogenetic techniques. The laboratory offers chromosome analysis of blood (peripheral blood and umbilical cord), amniotic fluid, chorionic villi, products of conception and skin fibroblasts. The laboratory also offers chromosomal analysis of bone marrow samples from hematological malignancies. These include acute leukemia, chronic myeloid leukemia, myelodysplastic syndrome (MDS), myeloproliferative disorders (MPD), multiple myeloma (MM), and chronic lymphocytic leukemia (CLL).

Prenatal/Postnatal molecular cytogenetic tests include fluorescence in situ hybridization (FISH) for AneuVysion (for detection of trisomy 13, 18, 21 and sex chromosome aneuploidy in amniotic fluid samples) and microdeletion syndromes (Prader Willi syndrome, DiGeorge Syndrome etc). Panel FISH assays for MM, CLL, MPD, MDS and other FISH tests for specific leukemia are also offered in the laboratory.