Jai S. Perumal, M.D.
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Jai S. Perumal, M.D.


Profile Photo of Jai S. Perumal, M.D.
Accepts New Patients
Gender: Female
Language: English


Specialties and Expertise


  • General Neurology


  • Multiple Sclerosis
  • Optic Neuritis
  • Neuromyelitis Optica
  • Neurosarcoidosis



Jai S. Perumal, M.D., is an Assistant Professor in the Department of Neurology and Neuroscience at Weill Cornell Medicine and Attending Neurologist at New York-Presbyterian Hospital/Weill Cornell Medicine (NYPH/WCM). She is faculty at the Weill Cornell Multiple Sclerosis Center at NYPH/WCM. She is the Director of the Madlyn Borelli MS Center at Nyack Hospital. She is board certified in Neurology and has additional specialized fellowship training in demyelinating disorders including multiple sclerosis.


Dr. Perumal received her medical degree from Stanley Medical College in India. She completed her internship in internal medicine and residency in neurology at Wayne State University in Detroit, Michigan. She was chief resident in neurology. She then completed her two year fellowship in clinical neuro-immunology and multiple sclerosis at Wayne State University. She is a recipient of the Sylvia Lawry Fellowship of the National Multiple Sclerosis Society. She is a Feil Family Clinical Scholar in Multiple Sclerosis at Weill Cornell Medicine.


She has presented at several neurology meetings and conferences and has published in peer-reviewed journals. Dr. Perumal's research interests include studying disease phenotypes, therapeutics and ethnic influences on disease characteristics in MS and MS variants including Devic's disease or neuromyelitis optica and central nervous system manifestations of systemic autoimmune diseases like SLE, sarcoidosis.




Kocsik AS, Klein DE, LiedkeM, Kaunzner UW, Nealon N, Gauthier SA, Vartanian TA, Perumal JS. Induction of disease remission with one cycle of alemtuzumab in relapsing–remitting MS. J Neurol. 2018 May;265(5):1226-1229.


Ranganathan U, Kaunzner U, Foster S, Vartanian T, Perumal J S. Thrombocytopenia at the time of alemtuzumab infusion in relapsing-remitting multiple sclerosis. Mult Scler. 2018 Apr;24(4):553-554


Ranganathan U, Kaunzner U,Foster SA,Vartanian T and Perumal JS. Immediate transient thrombocytopenia at the time of alemtuzumab infusion in multiple sclerosis. Mult Scler. 2018 Apr;24(4):540-542 


Kaunzner UW, Kumar G, Askin G,Gauthier SA, Nealon N, Vartanian T, Perumal JS. Study of patients with aggressive multiple sclerosis at disease onset. Neuropsychiatric Disease and Treatment 2016; 12:1907–1912


Fox RJ, Coffey CS, Conwit R, Cudkowicz ME, Gleason T, Goodman A, Klawiter EC, Matsuda K, McGovern M, Naismith RT, Ashokkumar A, Barnes J, Ecklund D, Klingner E, Koepp M, Long JD, Natarajan S, Thornell B, Yankey J, Bermel RA, Debbins JP, Huang X, Jagodnik P, Lowe MJ, Nakamura K, Narayanan S, Sakaie KE, Thoomukuntla B, Zhou X, Krieger S, Alvarez E, Apperson 1, Bashir K, Cohen BA, Coyle PK, Delgado S, Dewitt LD, Flores A, Giesser BS, Goldman MD, Jubelt B, Lava N, Lynch SG, Moses H, Ontaneda D, Perumal JS, Racke M, Repovic P, Riley CS, Severson C, Shinnar S, Suski V, Weinstock-Guttman B, Yadav V, Zabeti A. Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis.; NN102/SPRINT-MS Trial Investigators. N Engl J Med. 2018 Aug 30;379(9):846-855. doi: 10.1056/NEJMoa1803583.


Honors and Awards

Honors and Awards

2007-2009- Sylvia Lawry Fellow of the National Multiple Sclerosis Society


Board Certifications

  • American Board of Psychiatry & Neurology
  • American Board of Psychiatry & Neurology

Clinical and Academic Positions

  • Assistant Professor of Neurology - Weill Cornell Medical College, Cornell University
  • Assistant Attending Neurologist - NewYork-Presbyterian Hospital

Education and Training

  • M.B.,B.S., Stanley Medical College, Dr M.G.R Medical University (India), 1997


Insurance Plans Accepted

The following represents most of the managed care plans accepted by this doctor. If your insurance carrier does not appear here please contact the doctor’s office as they may have individual contracts not included on this site.

* indicates this doctor is no longer accepting new patients with this insurance plan.

  • AETNA - Medicare
  • Aetna Weill Cornell Employee Managed Care Plan
  • Aetna Weill Cornell Employee PPO Plan
  • Aetna-NYP - EPO/POS
  • Affinity Access
  • Affinity Health Plan
  • Emblem Select Care
  • Empire Blue Cross/Blue Shield - Blue Access
  • Empire Blue Cross/Blue Shield - Blue Connection
  • Empire Blue Cross/Blue Shield - EPO
  • Empire Blue Cross/Blue Shield - HMO
  • Empire Blue Cross/Blue Shield - Mediblue (Senior)
  • Empire Blue Cross/Blue Shield - PPO
  • Empire Blue Cross/Blue Shield HealthPlus
  • Empire Blue Cross/Blue Shield HealthPlus - CHP
  • Fidelis Care
  • GHI - CBP
  • Health First
  • Health Insurance Plan of NY (HIP) - Medicaid
  • Health Insurance Plan of NY (HIP) - Medicare
  • Health Insurance Plan of NY (HIP)
  • Medicaid
  • Medicare
  • Oxford Health Plans - Medicare Advantage
  • Oxford Health Plans - Metro/Core/Charter
  • Oxford Health Plans - Liberty
  • Oxford Health Plans - Freedom
  • Rockefeller University - Trustmark
  • United Empire
  • United Healthcare
  • United Healthcare - Community Plan
  • United Healthcare - Medicare
  • United Healthcare Compass
  • VNSNY CHOICE - Medicare
  • WorldWide Medical

Locations and Appointments

External Relationships

External Relationships

Relationships and collaborations with for-profit and not-for profit organizations are of vital importance to our faculty because these exchanges of scientific information foster innovation. As experts in their fields, WCM physicians and scientists are sought after by many organizations to consult and educate. WCM and its faculty make this information available to the public, thus creating a transparent environment.

Other Interest:
?; EMD Serono, Inc.