Peyronie's Disease

Peyronie’s disease is a condition where scar tissue (plaque) forms inside the penis, leading to curvature, painful erections and difficulty with penetration. While often linked to injury, other factors like autoimmune responses, genetics and even hormonal influences may contribute.

Symptoms & Emotional Impact of Peyronie’s Disease

Symptoms of Peyronie’s disease include:

• penile curvature.
• painful erections.
• in some cases, significant ED.

The severity varies, with some experiencing minor changes while others face significant deformity that makes penetration impossible. These changes can lead to frustration, loss of sexual confidence and psychological distress.

For members of the LGBTQ+ community, Peyronie’s disease may bring additional concerns, such as discomfort with discussing symptoms with healthcare providers and partners. Seeking a urologist can make a difference in both treatment outcomes and emotional well-being.

Causes and Risk Factors for Peyronie’s Disease

Peyronie’s disease can affect anyone assigned male at birth, but certain factors increase the risk, including:

• age: more common in individuals over 50 years old
• diabetes and Erectile Dysfunction (ED): reduced blood flow may contribute to scar formation
• prostate cancer surgery: up to 16% of post-surgical patients may develop Peyronie’s
• genetics and connective tissue disorders: conditions like Dupuytren’s contracture have been linked to Peyronie’s

Many people remain undiagnosed, with studies suggesting that up to one-third of those affected may not realize they have the condition.

Treatment Options for Peyronie’s Disease

Peyronie’s disease is treatable. Treatment options may include:

• medications and injections: collagenase (Xiaflex®) is FDA-approved to reduce curvature, with other options like verapamil or interferon injections also used
• penile traction therapy: a non-surgical option that helps improve curvature and minimize length loss
• surgery: for severe cases, options include penile plication (shortening the longer side), plaque excision with grafting or penile implants for those with ED

If you’re experiencing symptoms, don’t wait—early evaluation can improve treatment success.

Would You Like an Appointment?

To request an appointment or learn more about our program, please call our office at (646) 962-4811. Our phone staff is available Monday through Friday, 9 a.m. to 5 p.m. (EST).

Meet our expert provider who specializes in Peyronie's disease: