Peritoneal Surface Malignancy Program

Upper East Side
1315 York Avenue, 2nd Floor
New York, NY 10021
Mon-Fri 09:00am - 05:00pm

At Weill Cornell Medicine, the Peritoneal Surface Malignancy Program provides advanced, multidisciplinary care for patients with cancers that spread to the lining of the abdomen (the peritoneum). Our team specializes in diagnosing, treating, and supporting patients with rare and complex conditions, offering the latest treatment options, including cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).

Conditions We Treat

Our program at Weill Cornell Medicine focuses on a wide range of peritoneal surface cancers and related conditions, including:

  • Appendiceal cancer
  • Colorectal cancer with peritoneal metastases
  • Peritoneal mesothelioma
  • Pseudomyxoma peritonei (PMP)
  • Ovarian cancer with peritoneal spread
  • Gastric cancer with peritoneal involvement
  • Primary peritoneal carcinomatosis
  • Rare peritoneal tumors

Because these cancers behave differently than tumors in other organs, they require a highly specialized team with deep experience in both surgical and nonsurgical approaches.

Our Approach to Care

A Multidisciplinary Team

At Weill Cornell Medicine, every patient receives coordinated care from an expert group that may include:

  • Surgical oncologists
  • Medical oncologists
  • Radiologists
  • Pathologists
  • Oncology nurses
  • Nutrition specialists
  • Palliative care experts
  • Social workers and patient navigators

This collaborative approach ensures seamless, comprehensive care from diagnosis through survivorship.

Advanced Treatment Options

Cytoreductive Surgery (CRS)

This complex procedure removes visible tumors from the abdominal cavity. Our surgeons are highly experienced in performing extensive CRS procedures while prioritizing patient safety and long-term outcomes.

HIPEC (Heated Intraperitoneal Chemotherapy)

Following CRS, heated chemotherapy is circulated directly in the abdomen to target microscopic cancer cells. HIPEC allows for high‑dose, localized treatment with fewer systemic side effects.

Other treatment options include:

  • Systemic chemotherapy
  • Immunotherapy
  • Minimally invasive diagnostic procedures
  • Palliative surgical interventions
  • Supportive and symptom‑focused care

At Weill Cornell Medicine, we tailor each plan to the patient’s cancer type, stage, and overall health.

Why Choose Weill Cornell Medicine’s Peritoneal Surface Malignancy Program?

Experience That Matters

Our surgical team at Weill Cornell Medicine performs a high volume of CRS/HIPEC procedures each year—an important factor linked to improved outcomes and patient safety.

Comprehensive Pre‑ and Post‑Operative Support

From nutritional optimization to rehab and emotional support, we guide patients through every stage of their journey.

Innovative Research & Clinical Trials

Our team at Weill Cornell Medicine participates in ongoing research to advance the treatment of peritoneal surface malignancies and offer eligible patients access to clinical trials focused on novel therapies.

Personalized, Whole‑Patient Care

We understand that living with cancer affects every aspect of life. Our program is designed to support patients medically, emotionally, and practically.

What to Expect During Your First Visit

During your initial consultation, you will meet with members of our multidisciplinary care team to:

  • Review your medical history and imaging
  • Discuss your symptoms and concerns
  • Learn about potential treatment approaches
  • Receive a personalized care plan
  • Ask questions about surgery, recovery, and outcomes

We encourage patients to bring family members or caregivers to support the discussion and decision‑making process.

Support Services

To help you and your loved ones throughout treatment, we offer:

  • Patient navigation
  • Nutrition counseling
  • Behavioral health support
  • Pain and symptom management
  • Financial counseling
  • Support groups and survivorship resources

 

Make an Appointment

Our team is here to help you navigate your diagnosis and find the best path forward. Whether you visit us virtually through a video visit or you see us in person, you can be assured that we will deliver the highest standards of care with compassion. To make an appointment, please call (646) 962-2270 or complete our online appointment request form.

If you would like a remote second opinion, we can connect you directly with expert physicians and specialists at the Weill Cornell Medicine Colon and Rectal Surgery Division. They will review your individual situation, answer your questions and provide you with information you can share with your family and local practitioner. You can then decide to come to our facilities for treatment or choose to stay in your hometown and receive treatment locally. Learn more at WCM OnDemand Second Opinion. 

Meet our Surgeons

The physicians at the Weill Cornell Medicine’s Peritoneal Surface Malignancy Program offers patients the highest level of safety and care. As a top-ranked academic medical center, you have access to our extensive network of specialists who provide seamless care throughout your treatment — to promote long-term physical and mental health.

 

Our Doctors
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James Connolly, MD Profile Photo
Colon and Rectal Surgery 
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Mehraneh D. Jafari, M.D. Profile Photo
Colon and Rectal Surgery 
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