Mirella Salvatore, M.D.

Infectious Disease
Mirella Salvatore


1. Full papers  

1. Manna R., Salvatore M, Pantoli D., Vecchio F.M., Greco A.V., Carosella L., Schiavino D., Ghirlanda G.  (1988) Malignat histiocytosis.Report of three cases. British Journal of Clinical Practice 42,2: 82-86.  

  2. Manna R., Tafuri A., Salvatore M, Papa G., Altomonte L., Gambassi G. (1988) HLA e Malattie. I  Aspetti immunologici. Minerva Medico-Pratica 3:18-27.  

  3. Manna R., Tafuri A., Salvatore M, Ghirlanda G., Greco A.V., Gambassi G. (1988) HLA e Malattie. II  Aspetti Clinico-terapeutici. Minerva Medico-Pratica 4: 4-12.  

  4. Manna R., Salvatore M, Scuderi F., Tafuri A., Marietti G., Greco A.V., Ghirlanda G., Papa G. (1988)  Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis.Diabetes  research 3: 101-104.  

  5. Manna R., Salvatore M, Amato S., Ghirlanda G., Scuder F., Greco A.V. (1988) HLA antigens and islet  cell antibodies are useful for the identification of type 1 diabetes high risk subjects. Acta Med Romana  3:340-44.  

  6. Manna R., Migliore A., Salvatore M, Liang L., Micantonio L., Ponte E., Marietti G., Pantanella G., La  Valle C., Greco A.V., Ghirlanda G. (1990) Ridotta secrezione insulinica rivelata dall'IVGTT nei  consanguinei di primo grado di pazienti affetti da diabete insulino dipendente. Giornale Italiano di  Diabetologia 1:9-13.  

  7. Magalini S.C., Nanni G., Agnes S., Avolio A.W., Salvatore M, Manna R., Castagneto M.(1991).  Neopterin, amyloid A, C-reactive protein, gamma-interferon, and interleukin-2 receptor in diagnosis of  posttransplantation rejection. Transplant Proc. 23(4):2267-8.  

  8. Manna R., Salvatore M, Di Leo M.A.S., Scuderi F., Greco A.V., Ghirlanda G., Gambassi G. (1991)  Relationship between urinary neopterin excretion and islet cell antibodies in type 1 (insulin dependent)  diabetes. Diabetes research 17: 33-36.  

  9. Pocchiari M., Salvatore M., Ladogana A., Ingrosso L., Masullo C. (1991). Experimental drug treatment  of scrapie: a pathogenetic basis for scrapie pathogenesis. Eur J Epidemiol 7, 556-561.  

  10. Ladogana A., Casaccia P., Ingrosso L., Cibati M., Salvatore M., Xi Y.G., Masullo C., Pocchiari M.  (1992) Sulphate polyanions prolong the incubation period of scrapie-infected hamster. J Gen Virol, 73:  661-65.  

  11. Pocchiari M., Masullo C., Salvatore M., Genuardi M., Galgani S. (1992) Creutzfeldt-Jakob disease  after non-commercial dura graft. Lancet 340:614-15.  

  12. Pocchiari M., Salvatore M., Cotruzzola' F., Genuardi M., Travaglini-Allocatelli C. Masullo C., Macchi  G., Alema' G., Galgani S., Xi Y.G., Petraroli R., Silvestrini M.C., Brunori M. (1993) A new point mutation of  prion protein gene in Creutzfeldt-Jakob disease. Ann. Neurol. 34:802-807.  

  13. Masullo C., Salvatore M., Genuardi M., Pocchiari M., Macchi M. (1994) Progressive dementia in a  young patient with a homozygous deletion of PrP gene. Ann NY Acad Sci 724:358-360  


 14. Salvatore M., Genuardi M., Petraroli R., Masullo C,. D'alessandro M., Pocchiari M. (1995)  Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease. Hum Gen 94,  375-78.  

 15. Salvatore M., Seeber A.C., Nacmias B., Petraroli R., D'Alessandro M. Sorbi S,. Pocchiari M. (1995)  Apolipoprotein E in sporadic and familial Creutzfeldt-Jakob disease. Neurosci Lett 199(2):95-97.  

  16. Salvatore M., Pocchiari M., Cardone F., Petraroli R., D'Alessandro M., Galvez S., Brown P., Macchi  G., Fieschi C., Colosimo C. (1996) Codon 200 mutation in a new family of Chilean origin with Creutzfeldt- Jakob disease. J Neurol Neurosurg Psychiatry 61(1):111-2.  

 17. Barbanti P, Fabbrini G, Salvatore M, Petraroli R, Cardone F, Maras B, Equestre M, Macchi G, Lenzi  GL, Pocchiari M. (1996). Polymorphism at codon 129 or codon 219 of PRNP and clinical heterogeneity in  a previously unreported family with Gerstmann-Straussler-Scheinker disease (PrP-P102L mutation).  Neurology 47(3):734-41.  

  18. Salvatore M., Seeber A.C., Nacmias B., Petraroli R., Sorbi S., Pocchiari M. (1997). Alpha-1  antichymotrypsin signal peptide polymorphism in sporadic Creutzfeldt-Jakob disease. Neurosci Lett  227(2):140-2.  

  19. Salvatore M., Morzunov S, Schwemmle M, Lipkin WI. (1998) Borna disease virus in brains of North  American and European people with schizophrenia and bipolar disorder. Lancet 1349:9068  

  20. Schwemmle M*, Salvatore M* Shi L, Richt J, Lee CH, Lipkin WI. (1998) Interactions of the borna  disease virus P, N, and X proteins and their functional implications. J Biol Chem 273 (15): 9007-12. *  

equal contribution  

 21. Talon J, Salvatore M, O'Neill RE, Nakaya Y, Muster T, García-Sastre A, Palese P. (2000) Influenza A  and B viruses expressing altered NS1 proteins: A vaccine approach. PNAS 97 (8) 4309-14.  

  22. Basler C.F., Reid A.H., Dybing J.K., Janczewsky T.A., Fanning T.G., Zheng H., Salvatore M., Perdue  M.L., Swayne D.E., Garcia-Sastre A., Palese P., Taubemberger J.K. (2001) Sequence of the 1918  pandemic influenza virus non-structural gene (NS) segment and characterization of recombinant virus  bearing the 1918 NS genes. PNAS 98:2746-2751.  

  23. Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P,  Garcia-Sastre A. (2002) Effects of influenza A virus NS1 protein on protein expression: the NS1 protein  enhances translation and is not required for shutoff of host protein synthesis. J Virol 76 (3):1206-12.  

  24. Geiss GK*, Salvatore M*, Tumpey TM, Carter VS, Wang X, Basler CF, Taubenberger JK, Bumgarner  RE, Palese P, Katze MG, Garcia-Sastre A (2002) Cellular transcriptional profiling in influenza A virus- infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate  defense and its potential contribution to pandemic influenza. PNAS 99:10736-41. *

equal contribution  

  25. Bräu N, Salvatore M, Ríos-Bedoya CF, Fernández-Carbia A, Paronetto F, Rodríguez-Orengo JF,  and Rodríguez-Torres M. Slower Fibrosis Progression in HIV/HCV-Coinfected Patients with Successful  HIV Suppression Using Antiretroviral Therapy. J Hepatol. 2006 44(1): 47-55.  

  26. Salvatore M, García-Sastre A, Ruchala P, Lehrer RI, Chang T, Klotman ME. Alpha-Defensin Inhibitis  

Influenza Virus Replication By Cell Mediated Mechanism(s). JID 2007 196(6): 835-43.Epub 2007 Aug 10.  

 27. Negri D, Bona R, Michelini Z, Leone P, Macchia I, Klotman, ME, Salvatore M and Cara A. Transduction of human antigen presenting cells with integrase defective lentiviral vector enables functional expansion of primed antigen specific CD8 T cells. Hum Gene Ther. 2010 Mar 8. [Epub ahead of print]

28. Fusco D, Liu X, Savage C, Taur Y, Xiao W, Kennelly E, Yuan J, Cassileth B, Salvatore M, and Papanicolaou G. Echinacea Purpurea Aerial Extract Alters Course of Influenza Infection in Mice. Vaccine 2010 Apr 9. [Epub ahead of print]

 2. Book Chapters  

1. Ghirlanda G, Manna R, Salvatore M, Greco A V. (1989) Prediction of type 1 diabetes: the Rome family  study. in: Immunotherapy of type 1 diabetes. Ed:Andreani, Kolb, Pozzilli, cap 17, pp. 177-184, Wiley eds.  

  2. Manna R., Salvatore M. Gammpatie monoclonali e policlonali. in: Manuale di immunologia clinica.  9,101-105, Nuova Italia Scientifica ed. 1990.  

3. Salvatore M, Manna R. Le immunodeficienze. in: Manuale di immunologia clinica. 10,107-118, Nuova  Italia Scientifica ed. 1990.  

  4. Salvatore M, Pocchiari M. (1991) Biocontaminazione da virus lenti non convenzionali. Proceedings of  the V National Congress of the Association for the Study and Control of the Ambiental Pollution 165-186.  

 5. Salvatore M and Garcia-Sastre A.: Virus versus host: modulation of the host alpha/beta interferon  pathway by the influenza A virus NS1 protein. Excerpta Medical International Congress Series,  

  6. Meyers B and Salvatore M. Tetracylines and Chloramphenichol. In ‘Principles and Practice of  Infectious Diseases’ Eds Mandell, Douglas, Bennett, sixth edition, 2004  

  7. Salvatore M and Meyers B. Metronidazole. in ‘Principles and Practice of Infectious Diseases’ Eds  Mandell, Douglas, Bennett, sixth edition, 2004  

 8. Meyers B, Salvatore M. Aseptic meningitis. In ‘Clinical Infectious Diseases’, Ed Schlossberg, 2008

 9. Salvatore M and Meyers BTetracylines and Chloramphenichol. In ‘Principles and Practice of  Infectious Diseases’ Eds Mandell, Douglas, Bennett, 7th edition, 2009

  10. Salvatore M and Meyers B. Metronidazole. in ‘Principles and Practice of Infectious Diseases’ Eds  Mandell, Douglas, Bennett, 7th edition, 2009




Honors and Awards

2009 Top Cited Award 2006-2008 - Journal of Hepatology

2009 Member of the NIAID Influenza Research Collaboration-Combination Antiviral Focus Group