Ariel Elan Marciscano, M.D.

Radiation Oncology

Locations and Appointments

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Personal Statement

I am a board-certified radiation oncologist and physician-scientist working in both the clinic and lab to improve care for people with cancer.

I specialize in caring for people with cancer with a specific focus on genitourinary (prostate, bladder, kidney) cancers and metastatic cancers. My primary goals are to deliver excellent, compassionate, patient-centered care and to support my patients and their loved ones through their cancer treatment. I firmly believe that cancer care is not a one-size-fits-all approach. My philosophy is to educate and empower patients with information about their diagnosis so that they can confidently select a treatment plan that is individualized to their specific needs, personal preferences, and values.

I am deeply committed to improving the lives of people with cancer through research and have been involved in both lab research and clinical research for over a decade. At Weill Cornell Medicine, I serve as the Director of the Radiation Therapy Preclinical Core and my laboratory focuses on optimizing radiation-immunotherapy combinations. I am also involved in translational research and clinical trial efforts as part of an initiative to offer our patients cutting-edge technology and innovative treatments within the Department of Radiation Oncology at Weill Cornell Medicine.

Biographical Info

Dr. Ariel E. Marciscano is a board-certified radiation oncologist and Assistant Professor of Radiation Oncology at Weill Cornell Medicine/New York Presbyterian Hospital. He is a New York/New Jersey native. He received his undergraduate degree in Biology at Georgetown University where he was a Howard Hughes Medical Institute (HHMI) undegraduate research scholar. He received his M.D. from New York University School of Medicine during which time he studied radiosensitization of glioma via TGFbeta blockade in the Barcellos-Hoff laboratory. He completed a medical internship at Massachusetts General Hospital and residency training in radiation oncology at The Johns Hopkins Hospital. During his time at Johns Hopkins, Dr. Marciscano studied mechanisms of synergy of radiation and immunotherapy in the Bloomberg-Kimmel Institute for Cancer Immunotherapy in the laboratory of Charles G. Drake and subsequently completed a fellowship in Immunotherapy at the NCI, Center for Cancer Research. Dr. Marciscano joined the faculty at Memorial Sloan Kettering focusing on genitourinary cancers and metastatic disease with research initiatives in combining stereotactic radiation with immunotherapy for patients with metastatic cancer and developing novels methods to non-invasively treat and monitor response to stereotactic radiation. He has published several peer-reviewed manuscripts, review articles and book chapters and regularly presents his research at national and international scientific meetings.

Dr. Marciscano is currently a faculty member at Weill Cornell Medicine as Assistant Professor of Radiation Oncology. In his current role, he serves as Director of Radiation Therapy Preclinical Core (RTPC) and runs a research laboratory focusing on optimizing radiation-immunotherapy synergy, novel radiation-drug combinations and understanding the immune response to stereotactic radiation within the tumor microenvironment. He is also a member of the Radiation Oncology Clinical Research Office (ROCRO) providing a link between preclinical and clinical initiatives within the Department of Radiation Oncology.

Honors and Awards
  • Stand Up to Cancer (SU2C) Catalyst® Award – Young Investigator/Team Member (2019)
  • AACR/ASCO Methods in Clinical Cancer Research Workshop (2018)
  • SITC-NCI Immunotherapy Fellowship Award (2017)
  • RSNA R&E Foundation Research Fellow Grant (2017)
  • RSNA Roentgen Resident/Fellow Research Award, Johns Hopkins University (2017)
  • ASTRO Incorporating Radiation Oncology into Immunotherapy Committee (2017)
  • ASTRO Resident ePoster Recognition Award, Radiation and Cancer Biology (2017)
  • AACR Scholar-In-Training Award, Tumor Immunology & Immunotherapy (2016)
  • AACR Molecular Biology in Clinical Oncology (2016)
  • ASTRO Residents/Fellows in Radiation Oncology Research Seed Grant (2015)
Board Certifications
American Board of Radiology (Radiation Oncology)
Clinical Expertise
Stereotactic Radiation Therapy
Image-Guided Radiation Therapy
Intensity Modulated Radiation Therapy
Urologic Cancer
Metastatic Cancer
Prostate Cancer
Bladder Cancer
Kidney Cancer
Prostate Cancer, Advanced or Metastatic
Liver Metastases
Lung Metastases
Spine Tumors
  • M.D.
    New York University School of Medicine
  • B.S.
    Georgetown University
  • Adjunct Assistant Professor of Pathology and Laboratory Medicine (Courtesy)
    Weill Cornell Medical College, Cornell University

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No External Relationships Reported