Mark M. Souweidane, M.D.

Pediatric Neurological Surgery

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Biographical Info

Mark M. Souweidane, MD has dedicated his career to the surgical treatment of children with brain and spinal disorders. His talents as a surgeon are paralleled by a caring attitude and time commitment to patients and their families. That Weill Cornell Medicine is a recognized leader in Pediatric Neurosurgery is a direct result of his recruitment in 1995 and his ongoing devotion to contemporary surgical techniques and investigative endeavors. Specialized surgical skills have gained him international reputation for specific procedures, including removal of intraventricular brain tumors, management of pineal region tumors, treatment of congenital cysts, and surgery for Chiari malformation. In addition to the development of a world-class Pediatric Neurosurgery service, he has championed minimal access neurosurgery. His publications, clinical case volume, and practical courses continue to draw patients and practitioners that benefit from his endoscopic talents. His commitment to the education of future pediatric neurosurgeons is reflected in his participation on the Committee of Admissions for the medical college, his lectures to medical school students, his role as resident advisor, and resident mentoring at one of the country's premier training programs. Surgical areas of expertise include:

>> Removal of intraventricular brain tumors

>> Endoscopic intracranial surgery

>> Tumors (colloid cyst, benign astrocytoma)

>> Hydrocephalus (endoscopic third ventriculostomy)

>> Congenital cysts (endoscopic fenestration)

>> Treatment for Chiari malformations and syringomyelia

>> Management of pineal region tumors

>> Removal of intramedullary spinal cord tumors

>> Correction of craniofacial disorders

>> Multidisciplinary treatment of pediatric vascular abnormalities (arteriovenous malformations, Moyamoya disease, and cavernous malformations)

Dr. Souweidane currently serves as the Vice Chair of the Department of Neurological Surgery and the Director of Pediatric Neurological Surgery at NewYork-Presbyterian/Weill Cornell Medical Center and Memorial Sloan-Kettering Cancer Center. He is a professor in Neurological Surgery and Pediatrics.


Dr. Souweidane sees patients at 1305 York Avenue (at 70th Street), Neurological Surgery, 9th Floor New York, NY 

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Dr. Mark M. Souweidane completed his undergraduate training at the University of Michigan where he graduated with distinction in Microbiology. He attended Wayne State University Medical School as a member of the Alpha Omega Alpha Honor Society. His general surgery internship was completed at University of Michigan Hospitals and he subsequently did his neurosurgery residency at New York University under the direction of Drs. Joseph Ransohoff and Fred Epstein. He served as the chief clinical fellow for pediatric neurosurgery at the Hospital for Sick Children in Toronto during Harold Hoffman's tenure as chair.

He has gained international acclaim in minimally invasive endoscopic neurosurgery for the treatment of hydrocephalus, intraventricular brain tumors, colloid cysts, and congenital cysts. His other areas of expertise include brain and spinal cord tumors of childhood, Chiari malformations, congenital spinal disorders, arachnoid cysts, and pediatric vascular disorders. His commitment to advanced surgical therapy for children with brain tumors is exemplified by his appointment as Chair of the Neurosurgery Committee of the Children's Oncology Group. He is a member of the Professional Advisory Board of the Children's Brain Tumor Foundation. He has published 60 peer-reviewed articles, authored 6 book chapters, and serves on the editorial board of the journal Neurosurgery. He is the principal investigator of a laboratory that is partly funded by the Pediatric Brain Tumor Foundation. His laboratory focuses on improving the outcome of children with brain tumors by studying experimental local delivery and brain tumor modeling.



Weill Cornell Medicine Neurological Surgery

Dr. Souweidane's Neuro-oncology Laboratory

The Children's Brain Tumor Project

Honors and Awards
  • James B. Angell Scholar Recipient,    1982, 1983
  • Bachelors of Science Degree with High Honors,    1983
  • Medical Doctorate Degree with Distinction,    1988
  • Alpha Omega Alpha Inductee,    1988
  • Children’s Brain Tumor Foundation, Project Program Grant,    2000
  • Emily Dorfman Foundation for Children,    2001-2003
  • Save a Child’s Heart Foundation,    2003
  • Resident Teaching Award, Department of Neurological Surgery (NYPH-WMC),    2004, 2005
  • Isabel Gloria Neidorf Research Grant,    2004-2007
  • Beez Foundation Research Grant,    2005-2006
  • Lehman Brothers Foundation Award,    2006-2009
  • Children’s Hope Award,    2007
  • Pediatric Brain Tumor Foundation Research Grant,    2007-2008
  • Clinical & Translational Science Center Pilot Award,    2008
  • Nina W. Werblow Charitable Trust Award,    2009
  • Consumers’ Research Council of America Top Surgeons Award,    2010
  • Beez Foundation Research Grant,    2010
  • The Cure Starts Now Foundation Research Grant,    2010
  • The Cristian Rivera Foundation Award,    2010
  • Dana Neuroimmnology Foundation,    2010
  • St. Baldrick’s Foundation,    2010
  • Employee of the Year for Department of Neurological Surgery (NYPH-WMC),    2010, 2011
  • Cristian Rivera Vision of Hope Award,    2012, 2013, 2014
  • New York Magazine’s Best Doctors,    2012-2014
  • Louis and Rachel Rudin Foundation, Inc.,    2012-2014
  • Castle Connolly Best Doctors (nationwide),    2010-2015
  • McKenna Claire Foundation Research Grant,    2014
  • Cristian Rivera Vision of Hope Award,    2014
  • Chiari & Syringomyelia Foundation Award,    2015
  • New York Magazine’s Best Doctors,    2016 
  • Breakthrough Spirit Award, Children’s Cancer & Blood Foundation,    2016
  • Cristian Rivera Foundation Vison of Hope Award,    2016
  • Brain Tumor Foundation Award,    2016
  • TSC NYC Marathon Finisher: 5:05:44,    2018
  • Castle Connolly Top Doctors (New York Metro Area),    2004-2019
  • New York SuperDoctors 2008, 2009, 2012-2019
Board Certifications
American Board of Neurological Surgery
American Board of Pediatric Neurological Surgery
Clinical Expertise
Pediatric Brain Tumors
Minimally Invasive (Endoscopic) Neurosurgery
Craniofacial Disorders
Colloid Cyst of Third Ventricle
Pediatric Neuro-Oncology
Pontine Glioma
Pineal Tumor
Tethered Cord
Chiari Malformation
Spinal Cord Tumor
Pediatric Seizures
Endoscopic Neurosurgery
Arnold-Chiari Malformation
Craniofacial Abnormalities
Moyamoya Syndrome
Minimally Invasive Surgery
Pediatric Epilepsy Surgery
Pediatric Head and Neck Tumors
Pediatric Hydrocephalus
Pediatric Solid Tumors
Pediatric Stroke
Congenital Hydrocephalus
Hydrocephalus In Newborn
Hydrocephalus, Congenital
Intraventricular Endoscopic Neurosurgery
Brain Surgery
Pediatric Craniofacial Surgery
Craniofacial Anomaly
  • M.D.
    Wayne State University School of Medicine
  • Professor of Neurological Surgery in Pediatrics
    Weill Cornell Medical College, Cornell University
  • Professor of Neurological Surgery
    Weill Cornell Medical College, Cornell University
  • Attending Neurological Surgeon
    NewYork-Presbyterian Hospital
  • Adjunct Clinical Professor of Neurological Surgery
    Columbia University College of Physicians and Surgeons

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