Mario F.L. Gaudino, M.D., Ph.D.
Cardiac Surgery
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Mario F.L. Gaudino, M.D., Ph.D.

Cardiac Surgery

Profile Photo of Mario F.L. Gaudino, M.D., Ph.D.
Accepts New Patients
Video Visit Icon Video Visits Available
Gender: Male
Language: English, Italian


Personal Statement

“I am humbled to be an Attending Cardiac Surgeon in the Department of Cardiothoracic Surgery at Weill Cornell Medicine. Throughout my academic career, I have been lucky enough to train with the giants of coronary artery bypass surgery. While bypass surgery may appear as one of the more basic cardiac operation, the complexities of the patient and the variations of the operation require exquisite attention to detail to keep patients safe, which is my main priority. With the support of the incredible staff, including the cardiac anesthesia team, nurses, technicians and surgeons, I have the utmost confidence that I am in the best possible environment to provide the highest level of care to my patients.”

Specialties and Expertise


  • Cardiothoracic Surgery
  • Cardiac Surgery
  • Adult Cardiac Surgery
  • Heart Surgery


  • Coronary Bypass Surgery
  • Cardiac Bypass Surgery
  • Open Heart Surgery
  • Aortic Aneurysm Surgery
  • Aortic and Mitral Valve Surgery
  • Repair Aortic Dissection and Aneurysm
  • Surgery, Cardiac, Minimally Invasive
  • Mitral Valve Surgery
  • Repair of Cardiac Aneurysm
  • Surgical Removal of Aneurysm of Cardiac Conduit
  • Cardiac Valve Surgery
  • Aneurysmectomy of Heart
  • Thoracoabdominal Aortic Aneurysm Surgery
  • Bloodless Cardiothoracic Surgery
  • Mitral/Aortic Valve Replacement
  • Aortic Stent Graft
  • Aortic Arch Surgery
  • Aortic Aneurysm
  • Surgical Repair, Aortic Dissection
  • Aortic Aneurysm Repair
  • Ascending Aortic Aneurysm
  • Thoracic Aneurysm Repair
  • CABG (Coronary Artery Bypass Graft)


Dr. Gaudino completed his undergraduate studies and earned his medical degree in Rome, Italy at the University of Rome, Faculty of Medicine and Surgery in 1994. He subsequently completed his residency in 1999 at the same University and joined the faculty there in 2000 where he remained until 2014, when he joined the Department of Cardiothoracic Surgery at Weill Cornell Medicine. He completed an Advanced Cardiovascular/Aortic Aneurysm Surgery Fellowship in 2016 and was recruited to stay on staff as Attending Cardiothoracic Surgeon at NewYork Presbyterian|Weill Cornell Medicine and in 2017 he was elevated to the position of Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery (II).

In addition to his clinical expertise, Dr. Gaudino is currently the Assistant Dean for Clinical Trials, Director for the Joint Clinical Trials Office (JCTO), and the Director of Translational and Clinical Research for the Department of Cardiothoracic Surgery at Weill Cornell Medicine.  In his role, Dr. Gaudino oversees ongoing clinical trials and provides strategic growth plans to increase investigator-initiated trials, pragmatic trials, and ongoing improvements and enhancements to the existing clinical trial infrastructure.

Throughout his academic career, Dr. Gaudino has published more than 500 peer-reviewed manuscripts in cardiothoracic surgery, cardiology, and public health fields in high impact journals including first author in the New England Journal of Medicine, the Lancet and the Journal of the American Medical Association as well as numerous book chapters. He is currently the lead investigator of an international, randomized, controlled trial which aims to determine the optimal strategy for coronary artery bypass surgery (the ROMA trial) and STICH3C, an international, randomized controlled trial that will be the first in comparing the outcomes of PCI and CABG in patients with low ejection fraction. He recently completed a significant study that demonstrated the benefits of posterior left pericardiotomy for the prevention of postoperative atrial fibrillation in cardiac surgery patients. He is a frequently invited speaker at national and international meetings to share his exquisite knowledge of coronary artery bypass surgery and the use of multiple arterial grafts.

Dr. Gaudino currently serves as the Chair of the Coronary Artery Surgery Task Force of the European Association for Cardio-thoracic Surgery as well as the Chair of the Participant User File (PUF) Review Task Force of the Society of Thoracic Surgeons (Adult Cardiac Subcommittee).  He also serves the Vice-Chair of the AHA Council on Cardiovascular Surgery and Anesthesia CVSA Education and Publications Committee.

As a known advocate for scientific integrity and surgical quality, Dr. Gaudino is often called upon to serve on guideline writing committees to help set standards for cardiac surgery both nationally and internationally. Recently, Dr. Gaudino served as Chair of the writing committee for Methodological Standards for the Design, Implementation, and Analysis of Randomized Trials in Cardiac Surgery: A Scientific Statement From the American Heart Association.

Dr. Gaudino’s interests include all aspects of adult cardiac surgery. Along with his expert training and knowledge in coronary artery bypass surgery, including the use of multiple arterial grafting (radial artery conduits, the use of bilateral internal mammary arteries), Dr. Gaudino also specializes in structural heart disease, valvular dysfunction and complex aortic procedures. 



Clinical and Academic Positions

  • Professor of Cardiothoracic Surgery - Weill Cornell Medical College, Cornell University
  • Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery II - Weill Cornell Medical College, Cornell University

Education and Training

  • M.D., University of Rome Faculty of Medicine and Surgery (Italy), 1994


Insurance Plans Accepted

The following represents most of the managed care plans accepted by this doctor. If your insurance carrier does not appear here please contact the doctor’s office as they may have individual contracts not included on this site.

* indicates this doctor is no longer accepting new patients with this insurance plan.

  • AETNA - Medicare
  • Aetna Weill Cornell Employee Managed Care Plan
  • Aetna Weill Cornell Employee PPO Plan
  • Aetna-NYP - EPO/POS
  • Affinity Access
  • Affinity Health Plan
  • AgeWell New York
  • Amida Care
  • Emblem Select Care
  • Empire Blue Cross/Blue Shield - Blue Access
  • Empire Blue Cross/Blue Shield - Blue Connection
  • Empire Blue Cross/Blue Shield - EPO
  • Empire Blue Cross/Blue Shield - HMO
  • Empire Blue Cross/Blue Shield - Mediblue (Senior)
  • Empire Blue Cross/Blue Shield - PPO
  • Empire Blue Cross/Blue Shield HealthPlus
  • Empire Blue Cross/Blue Shield HealthPlus - CHP
  • Fidelis Care
  • Health First
  • Health Insurance Plan of NY (HIP)
  • Health Insurance Plan of NY (HIP) - Medicaid
  • Health Insurance Plan of NY (HIP) - Medicare
  • Medicaid
  • Medicare
  • Oxford Health Plans - Freedom
  • Oxford Health Plans - Liberty
  • Oxford Health Plans - Medicare Advantage
  • Oxford Health Plans - Metro/Core/Charter
  • Rockefeller University - Trustmark
  • United Empire
  • United Healthcare
  • United Healthcare - Community Plan
  • United Healthcare - Medicare
  • United Healthcare Compass
  • VNSNY CHOICE - Medicare
  • WellCare of NY
  • WorldWide Medical

Locations and Appointments

External Relationships

External Relationships

Relationships and collaborations with for-profit and not-for profit organizations are of vital importance to our faculty because these exchanges of scientific information foster innovation. As experts in their fields, WCM physicians and scientists are sought after by many organizations to consult and educate. WCM and its faculty make this information available to the public, thus creating a transparent environment.

No External Relationships Reported