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Coronary Microvascular Dysfunction (CMD) is an underrecognized cause of angina and myocardial ischemia in patients without significant blockages in the major coronary arteries. At Weill Cornell Medicine our team is dedicated to tailoring individualized care plans that combine precision diagnostics, evidence-based medical therapy, and shared decision-making to improve symptoms and long-term outcomes for those with CMD. As part of an academic institution, our program also contributes to clinical education and research efforts to enhance understanding and treatment of CMD and related ischemic heart conditions.
Coronary microvascular dysfunction is a condition that affects the heart’s smallest blood vessels. These vessels are responsible for increasing blood flow to the heart when your body needs it—such as during exercise or stress. In CMD, the small vessels do not function properly, which can lead to symptoms such as chest discomfort, shortness of breath, fatigue, or reduced exercise tolerance, even when the major heart arteries appear normal. CMD is more common than once thought and is especially prevalent in women. CMD may be caused by a variety of factors such as high blood pressure, diabetes, high cholesterol, autoimmune conditions, smoking, and prolonged physical or emotional stress.
Coronary microvascular dysfunction can be diagnosed during a cardiac catheterization, a minimally invasive procedure allowing for direct evaluation of blood flow through the heart. During the procedure, a catheter is guided to the coronary arteries and contrast dye is injected. Even when the larger arteries look normal, specialized testing can be performed to measure how well the small blood vessels respond to medication and changes in blood flow. These advanced measurements help identify problems with the microcirculation that are not visible on standard imaging tests. The procedure is performed by our experienced interventional cardiologists and is designed to be safe, precise, and informative.
If diagnosed with CMD our program personalizes treatment and may include medications to improve blood vessel function, manage symptoms, and address contributing conditions, along with lifestyle guidance focused on your heart health.
To schedule an appointment to see one of our physicians with expertise in coronary microvascular dysfunction, please call (646) 962-5500.
If you are already an established patient, you may also request an appointment online using Weill Cornell CONNECT. We will make every effort to contact you within 24 hours.
Our staff is here to help coordinate your care. They will provide you with information on our physicians, their areas of expertise and help arrange for your visit and other testing when appropriate.
