Manikkam Suthanthiran, M.B.,B.S.
Nephrology
Publications
1. Anglicheau D, Muthukumar T, Hummel A, Ding R, Sharma VK, Dadhania D, Seshan SV, Schwartz JE, Suthanthiran M. Discovery and validation of a molecular signature for the noninvasive diagnosis of human renal allograft fibrosis. Transplantation. 2012 Jun 15;93(11):1136-46. PMID:22592886
2. Yang H, Cheng EY, Sharma VK, Lagman M, Chang C, Song P, Ding R, Muthukumar T, Suthanthiran M. Dendritic cells with TGF-ß1 and IL-2 differentiate naive CD4+ T cells into alloantigen-specific and allograft protective Foxp3+ regulatory T cells. Transplantation. 2012 Mar 27;93(6):580-8. PMID:22270834
3. Perni U, Sison C, Sharma V, Helseth G, Hawfield A, Suthanthiran M, August P. Angiogenic factors in superimposed preeclampsia: a longitudinal study of women with chronic hypertension during pregnancy. Hypertension. 2012 Mar;59(3):740-6. Epub 2012 Feb 6. PMID:22311907
4. Moskowitz-Kassai E, Mackelaite L, Chen J, Patel K, Dadhania DM, Gross SS, Chander P, Delaney V, Deng L, Chen L, Cui X, Suthanthiran M, Goligorsky MS. Excretion of anti-angiogenic proteins in patients with chronic allograft dysfunction. Nephrol Dial Transplant. 2012 Feb;27(2):494-7. Epub 2012 Jan 17. PMID:22253069
5. Webber A, Hambleton J, Chami A, Bang H, Seshan S, Sharma A, August P, Kapur S, Suthanthiran M, Dadhania D. Mean arterial blood pressure while awaiting kidney transplantation is associated with the risk of primary nonfunction. Transplantation. 2012 Jan 15;93(1):54-60. PMID:22105679
6. Bradley JA, Hardy M, Neuberger J, Sachs D, Suthanthiran M, Wood K, Monaco AP, Morris PJ. Transplantation: a report of progress. Transplantation. 2010 Dec 27;90(12):1245. PMID:21160404
7. Afaneh C, Muthukumar T, Lubetzky M, Ding R, Snopkowski C, Sharma VK, Seshan S, Dadhania D, Schwartz JE, Suthanthiran M. Urinary cell levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and acute rejection of human renal allografts. Transplantation. 2010 Dec 27;90(12):1381-7. PMID:21079547
8. Cheng EY, Sharma VK, Chang C, Ding R, Allison AC, Leeser DB, Suthanthiran M, Yang H. Diannexin decreases inflammatory cell infiltration into the islet graft, reduces β-cell apoptosis, and improves early graft function. Transplantation. 2010 Oct 15;90(7):709-16. PMID:20634785
9. Anglicheau D, Muthukumar T, Suthanthiran M. MicroRNAs: small RNAs with big effects. Transplantation. 2010 Jul 27;90(2):105-12. Review. PMID:20574417
10. Dadhania D, Snopkowski C, Ding R, Muthukumar T, Lee J, Bang H, Sharma VK, Seshan S, August P, Kapur S, Suthanthiran M. Validation of noninvasive diagnosis of BK virus nephropathy and identification of prognostic biomarkers. Transplantation. 2010 Jul 27;90(2):189-97. PMID:20526237
11. Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL; Immune Tolerance Network ST507 Study Group. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest. 2010 Jun;120(6):1836-47. doi: 10.1172/JCI39933. Epub 2010 May 24. PMID:20501946
12. Sis B, Mengel M, Haas M, Colvin RB, Halloran PF, Racusen LC, Solez K, Baldwin WM 3rd, Bracamonte ER, Broecker V, Cosio F, Demetris AJ, Drachenberg C, Einecke G, Gloor J, Glotz D, Kraus E, Legendre C, Liapis H, Mannon RB, Nankivell BJ, Nickeleit V, Papadimitriou JC, Randhawa P, Regele H, Renaudin K, Rodriguez ER, Seron D, Seshan S, Suthanthiran M, Wasowska BA, Zachary A, Zeevi A. Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups. Am J Transplant. 2010 Mar;10(3):464-71. Epub 2010 Jan 29. PMID:20121738
13. Hartono C, Muthukumar T, Suthanthiran M. Noninvasive diagnosis of acute rejection of renal allografts. Curr Opin Organ Transplant. 2010 Feb;15(1):35-41. Review. PMID:19935064
14. Aull MJ, Suthanthiran M. Transplantation: Personalizing induction therapy in kidney transplantation. Nat Rev Nephrol. 2009 Nov;5(11):619-20. PMID:19855425
15. Hartono C, Suthanthiran M. Transplantation: Pump it up: conserving a precious resource? Nat Rev Nephrol. 2009 Aug;5(8):433-4. PMID:19639014
16. Suthanthiran M, Gerber LM, Schwartz JE, Sharma VK, Medeiros M, Marion R, Pickering TG, August P. Circulating transforming growth factor-beta1 levels and the risk for kidney disease in African Americans. Kidney Int. 2009 Jul;76(1):72-80. Epub 2009 Mar 11. PMID:19279557
17. Anglicheau D, Sharma VK, Ding R, Hummel A, Snopkowski C, Dadhania D, Seshan SV, Suthanthiran M. MicroRNA expression profiles predictive of human renal allograft status. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5330-5. Epub 2009 Mar 16. PMID:19289845
18. Suthanthiran M, Hojo M, Maluccio M, Boffa DJ, Luan FL. Post-transplantation malignancy: a cell autonomous mechanism with implications for therapy. Trans Am Clin Climatol Assoc. 2009;120:369-88. PMID:19768190
19. August P, Sharma V, Ding R, Schwartz JE, Suthanthiran M. Transforming growth factor beta and excess burden of renal disease. Trans Am Clin Climatol Assoc. 2009;120:61-72. PMID:19768163
20. Bradley JA, Hardy M, Neuberger J, Sachs D, Suthanthiran M, Wood K, Monaco AP, Morris PJ. Transplantation: a report of progress. Transplantation. 2008 Dec 27;86(12):1635. PMID:19104394
21. Dadhania D, Snopkowski C, Ding R, Muthukumar T, Chang C, Aull M, Lee J, Sharma VK, Kapur S, Suthanthiran M. Epidemiology of BK virus in renal allograft recipients: independent risk factors for BK virus replication. Transplantation. 2008 Aug 27;86(4):521-8. PMID:18724220
22. Anglicheau D, Suthanthiran M. Noninvasive prediction of organ graft rejection and outcome using gene expression patterns. Transplantation. 2008 Jul 27;86(2):192-9. Review. PMID:18645476
23. Aull MJ, Suthanthiran M. Should hepatitis C virus infection be a contraindication to renal transplantation? Nat Clin Pract Nephrol. 2008 Jun;4(6):304-5. Epub 2008 Apr 1. PMID:18382436
24. Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DS, Hertl M, Goes NB, Wong W, Williams WW Jr, Colvin RB, Sykes M, Sachs DH. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2008 Jan 24;358(4):353-61. PMID:18216355
25. Suthanthiran M. Dual transplantation of kidneys from expanded criteria donors: maximizing the use of a scarce resource. Nat Clin Pract Nephrol. 2007 Dec;3(12):652-3. Epub 2007 Oct 9. PMID:17925804
26. Yang H, Ding R, Sharma VK, Hilaire FS, Lagman M, Li B, Thomas DA, Luo X, Song P, Stauffer C, August P, Suthanthiran M. Hyperexpression of Foxp3 and IDO during acute rejection of islet allografts. Transplantation. 2007 Jun 27;83(12):1643-7. Erratum in: Transplantation. 2007 Nov 27;84(10):1375. Thomas, Dolea A [corrected to Thomas, Dolca A]. PMID:17589350
27. Luo X, Tarbell KV, Yang H, Pothoven K, Bailey SL, Ding R, Steinman RM, Suthanthiran M. Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2821-6. Epub 2007 Feb 16. PMID:17307871
28. Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM. Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J Exp Med. 2007 Jan 22;204(1):191-201. Epub 2007 Jan 8. PMID:17210729
29. Thomas DA, Stauffer C, Zhao K, Yang H, Sharma VK, Szeto HH, Suthanthiran M. Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function. J Am Soc Nephrol. 2007 Jan;18(1):213-22. Epub 2006 Dec 6. PMID:17151329
30. August P, Suthanthiran M. Transforming growth factor beta signaling, vascular remodeling, and hypertension. N Engl J Med. 2006 Jun 22;354(25):2721-3. PMID:16790709
31. Hirsch HH, Suthanthiran M. The natural history, risk factors and outcomes of polyomavirus BK-associated nephropathy after renal transplantation. Nat Clin Pract Nephrol. 2006 May;2(5):240-1. PMID:16932431
32. Strom TB, Suthanthiran M. Transcriptional profiling to assess the clinical status of kidney transplants. Nat Clin Pract Nephrol. 2006 Mar;2(3):116-7. PMID:16932404
33. Muthukumar T, Dadhania D, Ding R, Snopkowski C, Naqvi R, Lee JB, Hartono C, Li B, Sharma VK, Seshan SV, Kapur S, Hancock WW, Schwartz JE, Suthanthiran M. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med. 2005 Dec 1;353(22):2342-51. PMID:16319383
34. Hirsch HH, Brennan DC, Drachenberg CB, Ginevri F, Gordon J, Limaye AP, Mihatsch MJ, Nickeleit V, Ramos E, Randhawa P, Shapiro R, Steiger J, Suthanthiran M, Trofe J. Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation. 2005 May 27;79(10):1277-86. Review. PMID:15912088
35. Luo X, Yang H, Kim IS, Saint-Hilaire F, Thomas DA, De BP, Ozkaynak E, Muthukumar T, Hancock WW, Crystal RG, Suthanthiran M. Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice. Transplantation. 2005 May 15;79(9):1091-6. PMID:15880049
36. Boffa DJ, Waka J, Thomas D, Suh S, Curran K, Sharma VK, Besada M, Muthukumar T, Yang H, Suthanthiran M, Manova K. Measurement of apoptosis of intact human islets by confocal optical sectioning and stereologic analysis of YO-PRO-1-stained islets. Transplantation. 2005 Apr 15;79(7):842-5. PMID:15818328
37. Kotsch K, Mashreghi MF, Bold G, Tretow P, Beyer J, Matz M, Hoerstrup J, Pratschke J, Ding R, Suthanthiran M, Volk HD, Reinke P. Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection. Transplantation. 2004 Jun 27;77(12):1866-75. PMID:15223905
38. Tatapudi RR, Muthukumar T, Dadhania D, Ding R, Li B, Sharma VK, Lozada-Pastorio E, Seetharamu N, Hartono C, Serur D, Seshan SV, Kapur S, Hancock WW, Suthanthiran M. Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney Int. 2004 Jun;65(6):2390-7. PMID:15149352
39. Boffa DJ, Luan F, Thomas D, Yang H, Sharma VK, Lagman M, Suthanthiran M. Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer. Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):293-300. PMID:14734482
40. Hartono C, Dadhania D, Suthanthiran M. Noninvasive diagnosis of acute rejection of solid organ transplants. Front Biosci. 2004 Jan 1;9:145-53. Review. PMID:14766354
41. Shi R, Yang J, Jaramillo A, Steward NS, Aloush A, Trulock EP, Alexander Patterson G, Suthanthiran M, Mohanakumar T. Correlation between interleukin-15 and granzyme B expression and acute lung allograft rejection. Transpl Immunol. 2004 Jan;12(2):103-8. PMID:14967307
42. Thomas D, Suthanthiran M. Optimal modes and targets of gene therapy in transplantation. Immunol Rev. 2003 Dec;196:161-75. Review. PMID:14617204
43. August P, Suthanthiran M. Transforming growth factor beta and progression of renal disease. Kidney Int Suppl. 2003 Nov;(87):S99-104. PMID:14531781
44. Maluccio M, Sharma V, Lagman M, Vyas S, Yang H, Li B, Suthanthiran M. Tacrolimus enhances transforming growth factor-beta1 expression and promotes tumor progression. Transplantation. 2003 Aug 15;76(3):597-602. PMID:12923450
45. Medeiros M, Sharma VK, Ding R, Yamaji K, Li B, Muthukumar T, Valderde-Rosas S, Hernandez AM, Muñoz R, Suthanthiran M. Optimization of RNA yield, purity and mRNA copy number by treatment of urine cell pellets with RNAlater. J Immunol Methods. 2003 Aug;279(1-2):135-42. PMID:12969554
46. Ding R, Suthanthiran M. Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK VP1 virus in urine. Transplantation. 2003 Jul 27;76(2):446. PMID:12883219
47. Dadhania D, Muthukumar T, Ding R, Li B, Hartono C, Serur D, Seshan SV, Sharma VK, Kapur S, Suthanthiran M. Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection. Transplantation. 2003 May 27;75(10):1752-4. PMID:12777869
48. Muthukumar T, Ding R, Dadhania D, Medeiros M, Li B, Sharma VK, Hartono C, Serur D, Seshan SV, Volk HD, Reinke P, Kapur S, Suthanthiran M. Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation. 2003 May 15;75(9):1565-70. PMID:12792516
49. Ding R, Li B, Muthukumar T, Dadhania D, Medeiros M, Hartono C, Serur D, Seshan SV, Sharma VK, Kapur S, Suthanthiran M. CD103 mRNA levels in urinary cells predict acute rejection of renal allografts. Transplantation. 2003 Apr 27;75(8):1307-12. PMID:12717221
50. Boffa DJ, Feng B, Sharma V, Dematteo R, Miller G, Suthanthiran M, Nunez R, Liou HC. Selective loss of c-Rel compromises dendritic cell activation of T lymphocytes. Cell Immunol. 2003 Apr;222(2):105-15. PMID:12826080
51. Luan FL, Ding R, Sharma VK, Chon WJ, Lagman M, Suthanthiran M. Rapamycin is an effective inhibitor of human renal cancer metastasis. Kidney Int. 2003 Mar;63(3):917-26. PMID:12631072
52. Thomas D, Yang H, Boffa DJ, Ding R, Sharma VK, Lagman M, Li B, Hering B, Mohanakumar T, Lakey J, Kapur S, Hancock WW, Suthanthiran M. Proapoptotic Bax is hyperexpressed in isolated human islets compared with antiapoptotic Bcl-2. Transplantation. 2002 Dec 15;74(11):1489-96. PMID:12490780
53. Ding R, Medeiros M, Dadhania D, Muthukumar T, Kracker D, Kong JM, Epstein SR, Sharma VK, Seshan SV, Li B, Suthanthiran M. Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation. 2002 Oct 15;74(7):987-94. PMID:12394843
54. Yang H, Thomas D, Boffa DJ, Ding R, Li B, Muthukumar T, Sharma VK, Lagman M, Luo GX, Kapur S, Liou HC, Hancock WW, Suthanthiran M. Enforced c-REL deficiency prolongs survival of islet allografts1. Transplantation. 2002 Aug 15;74(3):291-8. PMID:12177605
55. Luan FL, Hojo M, Maluccio M, Yamaji K, Suthanthiran M. Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy. Transplantation. 2002 May 27;73(10):1565-72. PMID:12042641
56. Li B, Hartono C, Ding R, Sharma VK, Kracker D, Dadhania D, Serur D, Mouradian J, Seshan S, Schwartz JE, Suthanthiran M. Renal allograft surveillance by mRNA profiling of urinary cells. Transplant Proc. 2001 Nov-Dec;33(7-8):3280-2. PMID:11750404
57. Li B, Hartono C, Ding R, Sharma VK, Ramaswamy R, Qian B, Serur D, Mouradian J, Schwartz JE, Suthanthiran M. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med. 2001 Mar 29;344(13):947-54. PMID:11274620
58. Maluccio M, Sharma V, Lagman M, Konijn G, Suthanthiran M. Angiotensin II receptor blockade: a novel strategy to prevent immunosuppressant-associated cancer progression. Transplant Proc. 2001 Feb-Mar;33(1-2):1820-1. PMID:11267528
59. Sharma VK, Li B, Ding R, Lagman M, Forbes RD, Zheng S, Guttmann RD, Suthanthiran M. MHC-independent allograft vascular disease: mRNA profile in the MHC congenic rat heterotopic cardiac transplant model. Transplant Proc. 2001 Feb-Mar;33(1-2):389-90. PMID:11266876
60. Maluccio MA, Rao J, Sharma V, Lagman M, Suthanthiran M. Dendritic cells armed with anti-CD3 mAbs reduce pulmonary metastases, prolong survival, and engender antitumor effector cells demonstrable by adoptive transfer. Ann Surg Oncol. 2000 Dec;7(10):771-6. PMID:11129426
61. Suthanthiran M. Renal transplantation: reaping the rewards of biomedical research. Curr Opin Nephrol Hypertens. 2000 Nov;9(6):597-8. Review. PMID:11128420
62. Suthanthiran M. Immunologic monitoring: implications for treatment of rejection. Transplant Proc. 2000 Nov;32(7):1493-4. PMID:11119802
63. Suthanthiran M. T-cell antigen recognition and costimulatory pathways: implications for the induction of transplantation tolerance. Transplant Proc. 2000 Nov;32(7):1451-2. PMID:11119786
64. August P, Leventhal B, Suthanthiran M. Hypertension-induced organ damage in African Americans: transforming growth factor-beta(1) excess as a mechanism for increased prevalence. Curr Hypertens Rep. 2000 Apr;2(2):184-91. Review. PMID:10981147
65. Suthanthiran M, Li B, Song JO, Ding R, Sharma VK, Schwartz JE, August P. Transforming growth factor-beta 1 hyperexpression in African-American hypertensives: A novel mediator of hypertension and/or target organ damage. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3479-84. PMID:10725360
66. Suthanthiran M. The importance of genetic polymorphisms in renal transplantation. Curr Opin Urol. 2000 Mar;10(2):71-5. Review. PMID:10785845
67. Strom TB, Suthanthiran M. Prospects and applicability of molecular diagnosis of allograft rejection. Semin Nephrol. 2000 Mar;20(2):103-7. PMID:10746854
68. Hojo M, Suthanthiran M, Helseth G, August P. Lymphocyte intracellular free calcium concentration is increased in preeclampsia. Am J Obstet Gynecol. 1999 May;180(5):1209-14. PMID:10329879
69. Hojo M, Morimoto T, Maluccio M, Asano T, Morimoto K, Lagman M, Shimbo T, Suthanthiran M. Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature. 1999 Feb 11;397(6719):530-4. PMID:10028970
70. Li B, Khanna A, Sharma V, Singh T, Suthanthiran M, August P. TGF-beta1 DNA polymorphisms, protein levels, and blood pressure. Hypertension. 1999 Jan;33(1 Pt 2):271-5. PMID:9931116
71. Ding R, Li B, Sharma VK, Bologa RM, Lagman M, Mouradian J, Strom TB, Suthanthiran M. Quantitative competitive polymerase chain reaction: design and synthesis of mRNA-specific competitor DNA templates and their clinical usage. Transplant Proc. 1998 Aug;30(5):2370-2. PMID:9723508
72. Sharma VK, Ding R, Li B, Bologa RM, Lagman M, Eduafo A, Edouard P, Mouradian J, Strom TB, Suthanthiran M. Molecular correlates of human renal allograft rejection. Transplant Proc. 1998 Aug;30(5):2364-6. PMID:9723506
73. Suthanthiran M, Khanna A, Cukran D, Adhikarla R, Sharma VK, Singh T, August P. Transforming growth factor-beta 1 hyperexpression in African American end-stage renal disease patients. Kidney Int. 1998 Mar;53(3):639-44. PMID:9507209
74. Shin GT, Khanna A, Ding R, Sharma VK, Lagman M, Li B, Suthanthiran M. In vivo expression of transforming growth factor-beta1 in humans: stimulation by cyclosporine. Transplantation. 1998 Feb 15;65(3):313-8. PMID:9484745
75. Suthanthiran M, Strom TB. Mechanisms and management of acute renal allograft rejection. Surg Clin North Am. 1998 Feb;78(1):77-94. Review. PMID:9531937
76. Suthanthiran M. Human renal allograft rejection: molecular characterization. Nephrol Dial Transplant. 1998;13 Suppl 1:21-4. PMID:9507493
77. Suthanthiran M, Strom TB. Immunoregulatory drugs: mechanistic basis for use in organ transplantation. Pediatr Nephrol. 1997 Oct;11(5):651-7. Review. PMID:9323301
78. Asano T, Khanna A, Lagman M, Li B, Suthanthiran M. Immunostimulatory therapy with anti-CD3 monoclonal antibodies and recombinant interleukin-2: heightened in vivo expression of mRNA encoding cytotoxic attack molecules and immunoregulatory cytokines and regression of murine renal cell carcinoma. J Urol. 1997 Jun;157(6):2396-401. PMID:9146677
79. Suthanthiran M. Clinical application of molecular biology: a study of allograft rejection with polymerase chain reaction. Am J Med Sci. 1997 May;313(5):264-7. PMID:9145034
80. Khanna A, Kapur S, Sharma V, Li B, Suthanthiran M. In vivo hyperexpression of transforming growth factor-beta1 in mice: stimulation by cyclosporine. Transplantation. 1997 Apr 15;63(7):1037-9. PMID:9112364
81. Suthanthiran M. Acute rejection of renal allografts: mechanistic insights and therapeutic options. Kidney Int. 1997 Apr;51(4):1289-304. Review. PMID:9083299
82. AndjelÃc S, Khanna A, Suthanthiran M, Nikolić-Zugić J. Intracellular Ca2+ elevation and cyclosporin A synergistically induce TGF-beta 1-mediated apoptosis in lymphocytes. J Immunol. 1997 Mar 15;158(6):2527-34. PMID:9058783
83. Suthanthiran M. Molecular analyses of human renal allografts: differential intragraft gene expression during rejection. Kidney Int Suppl. 1997 Mar;58:S15-21. PMID:9067937
84. Sharma VK, Bologa RM, Li B, Xu GP, Lagman M, Mouradian J, Wang J, Serur D, Rao VK, Suthanthiran M. Intrarenal display of cytotoxic attack molecules during rejection. Transplant Proc. 1997 Feb-Mar;29(1-2):1090-1. PMID:9123214
85. Shin GT, Khanna A, Sharma VK, Ding R, Azizlerli S, Li B, Suthanthiran M. In vivo hyperexpression of transforming growth factor-beta 1 in humans: stimulation by cyclosporine. Transplant Proc. 1997 Feb-Mar;29(1-2):284. PMID:9122996
86. Shin GT, Cheigh JS, Riggio RR, Suthanthiran M, Stubenbord WT, Serur D, Wang JC, Rubin AL, Stenzel KH. Effect of nifedipine on renal allograft function and survival beyond one year. Clin Nephrol. 1997 Jan;47(1):33-6. PMID:9021239
87. Sharma VK, Bologa RM, Li B, Xu GP, Lagman M, Hiscock W, Mouradian J, Wang J, Serur D, Rao VK, Suthanthiran M. Molecular executors of cell death--differential intrarenal expression of Fas ligand, Fas, granzyme B, and perforin during acute and/or chronic rejection of human renal allografts. Transplantation. 1996 Dec 27;62(12):1860-6. PMID:8990377
88. Suthanthiran M. Transplantation tolerance: fooling mother nature. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12072-5. Review. PMID:8901533
89. Suthanthiran M, Morris RE, Strom TB. Immunosuppressants: cellular and molecular mechanisms of action. Am J Kidney Dis. 1996 Aug;28(2):159-72. Review. PMID:8768909
90. Khanna A, Li B, Sharma VK, Suthanthiran M. Immunoregulatory and fibrogenic activities of cyclosporine: a unifying hypothesis based on transforming growth factor-beta expression. Transplant Proc. 1996 Aug;28(4):2015-8. Review. PMID:8769140
91. Kapur S, Khanna A, Sharma VK, Li B, Suthanthiran M. CD2 antigen targeting reduces intragraft expression of mRNA-encoding granzyme B and IL-10 and induces tolerance. Transplantation. 1996 Jul 27;62(2):249-55. PMID:8755824
92. Strom TB, Suthanthiran M. Therapeutic approach to organ transplantation. Nephrol Dial Transplant. 1996 Jun;11(6):1176-81. Review. PMID:8671995
93. Shin GT, Cheigh JS, Riggio RR, Suthanthiran M, Stubenbord WT, Serur D, Wang JC, Rubin A, Stenzel KH. Long-term beneficial effects of a nifedipine-supplemented immunosuppressive regimen in kidney transplantation. Transplant Proc. 1996 Jun;28(3):1309-10. PMID:8658672
94. Sharma VK, Bologa RM, Xu GP, Li B, Mouradian J, Wang J, Serur D, Rao V, Suthanthiran M. Intragraft TGF-beta 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy. Kidney Int. 1996 May;49(5):1297-303. PMID:8731094
95. Khanna A, Li B, Li P, Suthanthiran M. Transforming growth factor-beta 1: regulation with a TGF-beta 1 antisense oligomer. Kidney Int Suppl. 1996 Jan;53:S2-6. PMID:8770984
96. Kapur S, Sharma V, Khanna A, Li B, Sukol K, Suthanthiran M. Regulation of the anti-allograft response by targeting the CD2 antigen: a potential strategy for the creation of transplant tolerance. Surg Technol Int. 1996;5:233-40. PMID:15858746
97. Suthanthiran M. Transmembrane signaling requirements of T cells: implications for regulation of alloimmunity. Transplant Proc. 1995 Oct;27(5 Suppl 1):5-7. Review. PMID:7482822
98. Suthanthiran M, Strom TB. Immunobiology and immunopharmacology of organ allograft rejection. J Clin Immunol. 1995 Jul;15(4):161-71. Review. PMID:7593462
99. Jain K, Yang H, Cai BR, Haque B, Hurvitz AI, Diehl C, Miyata T, Smith BH, Stenzel K, Suthanthiran M, et al. Retrievable, replaceable, macroencapsulated pancreatic islet xenografts. Long-term engraftment without immunosuppression. Transplantation. 1995 Feb 15;59(3):319-24. PMID:7871558
100. Prashar Y, Khanna A, Sehajpal P, Sharma VK, Suthanthiran M. Stimulation of transforming growth factor-beta 1 transcription by cyclosporine. FEBS Lett. 1995 Jan 23;358(2):109-12. PMID:7828718
101. Jain K, Cai BR, Patel S, Yang H, Smith BH, Suthanthiran M, Rubin AL. Consistent long-term allograft survival in murine pancreatic islet transplants without immunosuppression. Transplant Proc. 1994 Dec;26(6):3492-3. PMID:7998243
102. Jain K, Cai BR, Patel S, Anderson M, Miller D, Smith BH, Rubin AL, Suthanthiran M. Class I major histocompatibility complex antigen disparity is not a barrier to successful pancreatic islet cell engraftment. Transplant Proc. 1994 Dec;26(6):3323-4. PMID:7998155
103. Khanna A, Li B, Li P, Suthanthiran M. Regulation of transforming growth factor-beta 1 (TGF-beta 1) expression with a novel TGF-beta 1 complementary DNA. Biochem Biophys Res Commun. 1994 Nov 15;204(3):1061-6. PMID:7980578
104. Sharma VK, Li B, Khanna A, Sehajpal PK, Suthanthiran M. Which way for drug-mediated immunosuppression? Curr Opin Immunol. 1994 Oct;6(5):784-90. Review. PMID:7826535
105. Nakajima F, Khanna A, Xu G, Lagman M, Haschemeyer R, Mouradian J, Wang JC, Stenzel KH, Rubin AL, Suthanthiran M. Immunotherapy with anti-CD3 monoclonal antibodies and recombinant interleukin 2: stimulation of molecular programs of cytotoxic killer cells and induction of tumor regression. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):7889-93. PMID:8058730
106. Suthanthiran M, Strom TB. Renal transplantation. N Engl J Med. 1994 Aug 11;331(6):365-76. Review. PMID:7832839
107. Nakajima F, Nakamura H, Stenzel KH, Suthanthiran M. Involvement of tumor necrosis factor in development of anti-CD3 monoclonal antibody induced pulmonary edema. Transplant Proc. 1994 Aug;26(4):1939-40. PMID:8066628
108. Khanna A, Li B, Stenzel KH, Suthanthiran M. Regulation of new DNA synthesis in mammalian cells by cyclosporine. Demonstration of a transforming growth factor beta-dependent mechanism of inhibition of cell growth. Transplantation. 1994 Feb 27;57(4):577-82. PMID:8116045
109. Zuckerman AL, Stenzel KH, Suthanthiran M, Holthofer H, Schlondorff D. Modulation of mouse mesangial cell proliferation by thiourea and lipoxygenase inhibitors. Nephron. 1994;66(3):337-43. PMID:8190188
110. Imani F, Horii Y, Suthanthiran M, Skolnik EY, Makita Z, Sharma V, Sehajpal P, Vlassara H. Advanced glycosylation endproduct-specific receptors on human and rat T-lymphocytes mediate synthesis of interferon gamma: role in tissue remodeling. J Exp Med. 1993 Dec 1;178(6):2165-72. PMID:8245789
111. Ingulli E, Sharma V, Singh A, Suthanthiran M, Tejani A. Steroid withdrawal, rejection and the mixed lymphocyte reaction in children after renal transplantation. Kidney Int Suppl. 1993 Oct;43:S36-9. PMID:8246367
112. Suthanthiran M. Signaling features of T cells: implications for the regulation of the anti-allograft response. Kidney Int Suppl. 1993 Oct;43:S3-11. Review. PMID:7902466
113. Suthanthiran M, Haschemeyer RH, Riggio RR, Adubor C, Friedman GS, Cheigh JS, Wang JC, Fotino M, Stubenbord WT, Saal SD, et al. Excellent outcome with a calcium channel blocker-supplemented immunosuppressive regimen in cadaveric renal transplantation. A potential strategy to avoid antibody induction protocols. Transplantation. 1993 May;55(5):1008-13. PMID:8497873
114. Sehajpal PK, Sharma VK, Ingulli E, Stenzel KH, Suthanthiran M. Synergism between the CD3 antigen- and CD2 antigen-derived signals. Exploration at the level of induction of DNA-binding proteins and characterization of the inhibitory activity of cyclosporine. Transplantation. 1993 May;55(5):1118-24. PMID:8098881
115. Sharma VK, Sehajpal PK, Friedman GS, Stenzel KH, Suthanthiran M. Transmembrane signaling requirements of T cells. Transplant Proc. 1993 Apr;25(2 Suppl 1):7-9. PMID:8465431
116. Sehajpal PK, Sharma VK, Stenzel KH, Suthanthiran M. Two-signal model for T-cell activation: molecular mechanisms. Transplant Proc. 1993 Feb;25(1 Pt 1):104-5. PMID:8094907
117. Li B, Sehajpal PK, Subramaniam A, Joseph A, Stenzel KH, Suthanthiran M. Inhibition of interleukin 2 receptor expression in normal human T cells by cyclosporine. Demonstration at the mRNA, protein, and functional levels. Transplantation. 1992 Jan;53(1):146-51. PMID:1346344
118. Li B, Sehajpal PK, Khanna A, Vlassara H, Cerami A, Stenzel KH, Suthanthiran M. Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction. J Exp Med. 1991 Nov 1;174(5):1259-62. PMID:1682412
119. Yang Z, Makita Z, Horii Y, Brunelle S, Cerami A, Sehajpal P, Suthanthiran M, Vlassara H. Two novel rat liver membrane proteins that bind advanced glycosylation endproducts: relationship to macrophage receptor for glucose-modified proteins. J Exp Med. 1991 Sep 1;174(3):515-24. PMID:1651976
120. Walz G, Stevens C, Zanker B, Melton LB, Clark SC, Suthanthiran M, Strom TB. The role of interleukin-6 in mitogenic T-cell activation: detection of interleukin-2 heteronuclear RNA by polymerase chain reaction. Cell Immunol. 1991 May;134(2):511-9. PMID:1827050
121. Novogrodsky A, Suthanthiran M, Stenzel KH. Ferro-mitogens: iron-containing compounds with lymphocyte-stimulatory properties. Cell Immunol. 1991 Apr 1;133(2):295-305. PMID:2015630
122. Cheigh JS, Suthanthiran M, Fotino M, Riggio RR, Schechter N, Stubenbord WT, Rubin AL, Stenzel KH. Minimal sensitization and excellent renal allograft outcome following donor-specific blood transfusion with a short course of cyclosporine. Transplant Proc. 1991 Feb;23(1 Pt 2):1023. PMID:1989145
123. Li B, Sehajpal P, Estin D, Fotino M, Suthanthiran M. Signaling normal human T-cells: synergism between CD2 antigen and CD3/T cell receptor alpha beta complex in the elicitation of IL-2 and IL-2 receptor gene expression. Transplant Proc. 1991 Feb;23(1 Pt 1):77-8. PMID:1671306
124. Cheigh JS, Suthanthiran M, Fotino M, Riggio RR, Schechter N, Stubenbord WT, Stenzel KH, Rubin AL. Minimal sensitization and excellent renal allograft outcome following donor-specific blood transfusion with a short course of cyclosporine. Transplantation. 1991 Feb;51(2):378-81. PMID:1825244
125. Tejani A, Suthanthiran M, Pomrantz A. A randomized controlled trial of low-dose prednisone and ciclosporin versus high-dose prednisone in nephrotic syndrome of children. Nephron. 1991;59(1):96-9. PMID:1944755
126. Wieder KJ, Walz G, Zanker B, Sehajpal P, Sharma VK, Skolnik E, Strom TB, Suthanthiran M. Physiologic signaling in normal human T-cells: mRNA phenotyping by northern blot analysis and reverse transcription-polymerase chain reaction. Cell Immunol. 1990 Jun;128(1):41-51. PMID:1971531
127. Suthanthiran M. A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T cell receptor-alpha/beta complex with the cluster determinant 2 antigen. J Exp Med. 1990 Jun 1;171(6):1965-79. PMID:1972176
128. Suthanthiran M, Anderson ME, Sharma VK, Meister A. Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens. Proc Natl Acad Sci U S A. 1990 May;87(9):3343-7. PMID:1970635
129. Kinkhabwala M, Sehajpal P, Skolnik E, Smith D, Sharma VK, Vlassara H, Cerami A, Suthanthiran M. A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells. J Exp Med. 1990 Mar 1;171(3):941-6. PMID:2307938
130. Walz G, Zanker B, Melton LB, Suthanthiran M, Strom TB. Possible association of the immunosuppressive and B cell lymphoma-promoting properties of cyclosporine. Transplantation. 1990 Jan;49(1):191-4. PMID:2137272
131. Novogrodsky A, Suthanthiran M, Stenzel KH. Immune stimulatory properties of metalloporphyrins. J Immunol. 1989 Dec 15;143(12):3981-7. PMID:2512345
132. Wang JC, Walle A, Novogrodsky A, Suthanthiran M, Silver RT, Bander NH, Rubin AL, Stenzel KH. A phase II clinical trial of adoptive immunotherapy for advanced renal cell carcinoma using mitogen-activated autologous leukocytes and continuous infusion interleukin-2. J Clin Oncol. 1989 Dec;7(12):1885-91. PMID:2555451
133. Carpenter CB, Suthanthiran M. The prophylactic use of monoclonal antibodies in renal transplantation: a consensus conference sponsored by the American Society of Transplant Physicians. Am J Kidney Dis. 1989 Nov;14(5 Suppl 2):1-4. Review. PMID:2683756
134. Suthanthiran M, Fotino M, Riggio RR, Cheigh JS, Stenzel KH. OKT3-associated adverse reactions: mechanistic basis and therapeutic options. Am J Kidney Dis. 1989 Nov;14(5 Suppl 2):39-44. PMID:2530898
135. Sehajpal P, Subramaniam A, Murthi VK, Sharma VK, Suthanthiran M. Demonstration of a direct inhibitory effect of cyclosporine on normal human T-cells with two novel models of T-cell activation as probes. Cell Immunol. 1989 Apr 15;120(1):195-204. PMID:2522829
136. Yoon YS, Cheigh JS, Riggio RR, Stenzel KH, Suthanthiran M. Analysis of spontaneous blastogenesis profiles in recipients of renal allografts. Transplant Proc. 1989 Feb;21(1 Pt 2):1925. PMID:2652626
137. Suthanthiran M. Signaling via the T-cell antigen receptor heterodimer and the CD2 antigen: a novel, synergistic pathway for activation of T-cells. Transplant Proc. 1989 Feb;21(1 Pt 1):340-1. PMID:2565053
138. Suthanthiran M. Transmembrane signalling via the T cell antigen receptor heterodimer and the CD2 antigen. A synergistic pathway for activation of T cells. Transplantation. 1989 Feb;47(2):348-51. PMID:2563920
139. Subramaniam A, Sehajpal P, Murthi VK, Stenzel KH, Suthanthiran M. Activation of human T cells with the physiological regulator of protein kinase C. Cell Immunol. 1988 Oct 15;116(2):439-49. PMID:2902930
140. Suthanthiran M, Stenzel KH. Human memory T cell activation. Effects of monoclonal antibodies directed at interleukin-2, receptors for interleukin-2, or interferon-gamma. Transplantation. 1988 Aug;46(2):292-8. PMID:3136562
141. Suthanthiran M. Oxidative mitogenesis: participation of CD2 antigen in the generation and/or transduction of obligatory accessory signals. Cell Immunol. 1988 Jun;114(1):117-25. PMID:2897246
142. Suthanthiran M. T-cell differentiation antigen cluster 2 (CD2) is a receptor for accessory cells and can generate and/or transduce accessory signals. Cell Immunol. 1988 Mar;112(1):112-22. PMID:3257905
143. Walle AJ, Wong GY, Suthanthiran M, Rubin AL, Stenzel KH, Darzynkiewicz Z. Altered nucleic acid contents of mononuclear cells in blood of renal allograft recipients. Cytometry. 1988 Mar;9(2):177-82. PMID:2452058
144. Tejani AT, Butt K, Trachtman H, Suthanthiran M, Rosenthal CJ, Khawar MR. Cyclosporine A induced remission of relapsing nephrotic syndrome in children. Kidney Int. 1988 Mar;33(3):729-34. PMID:2966873
145. Walle AJ, Wong GY, Suthanthiran M, Rubin AL, Stenzel KH. In vivo effects of high-dose steroids on nucleic acid content of immunocompetent cells of renal allograft recipients. Transplantation. 1988 Mar;45(3):534-6. PMID:2450413
146. Walle AJ, Wang J, Novogrodsky A, Suthanthiran M, Gordon B, Rubin AL, Stenzel KH. Periodate and recombinant interleukin-2-activated autologous leukocytes can induce regression of metastases of renal cancer. Cancer Detect Prev. 1988;12(1-6):395-411. PMID:2846172
147. Wang J, Walle A, Gordon B, Novogrodsky A, Suthanthiran M, Rubin AL, Morrison H, Silver RT, Stenzel KH. Adoptive immunotherapy for stage IV renal cell carcinoma: a novel protocol utilizing periodate and interleukin-2-activated autologous leukocytes and continuous infusions of low-dose interleukin-2. Am J Med. 1987 Dec;83(6):1016-23. PMID:2845776
148. Tejani A, Butt K, Trachtman H, Suthanthiran M, Rosenthal CJ, Khawar MR. Cyclosporine-induced remission of relapsing nephrotic syndrome in children. J Pediatr. 1987 Dec;111(6 Pt 2):1056-62. PMID:3500297
149. Suthanthiran M. Inhibitory activity of cyclosporine is dependent on the activating signal(s) provided to T cells. J Pediatr. 1987 Dec;111(6 Pt 2):1008-11. PMID:2960793
150. Suthanthiran M, Wiebe ME, Stenzel KH. Effect of immunosuppressants on OKT3 associated T cell activation: clinical implications. Kidney Int. 1987 Sep;32(3):362-7. PMID:3118092
151. Walle AJ, Suthanthiran M, Darzynkiewicz Z, Rubin AL, Stenzel KH. Cell cycle analysis of activated mononuclear blood cells of renal allograft recipients. Transplant Proc. 1987 Feb;19(1 Pt 3):2183-4. PMID:3274487
152. Cheigh JS, Suthanthiran M, Stubenbord WT, Fotino M, Riggio RR, Schechter N, Stenzel KH, Rubin AL. Optimization of donor specific blood transfusion in kidney transplantation. Transplant Proc. 1987 Feb;19(1 Pt 3):2250-1. PMID:2978891
153. Suthanthiran M. Human T cell activation: participation of Tll antigen (CD2, T,gp.50) in T cell-accessory cell interactions. Transplant Proc. 1987 Feb;19(1 Pt 1):336-7. PMID:2908550
154. Wang J, Suthanthiran M, Walle A, Lagman M, Schwartz R, Murthi V, Novogrodsky A, Stenzel KH. Anti-tumor properties of lymphocytes activated by the oxidizing mitogens. J Immunol. 1986 Jun 15;136(12):4735-9. PMID:3011903
155. Miller IJ, Suthanthiran M, Riggio RR, Williams JJ, Riehle RA, Vaughan ED, Stubenbord WT, Mouradian J, Cheigh JS, Stenzel KH. Impact of renal donation. Long-term clinical and biochemical follow-up of living donors in a single center. Am J Med. 1985 Aug;79(2):201-8. PMID:3895908
156. Arnold A, Lipkowitz S, Suthanthiran M, Novogrodsky A, Stenzel KH. Human B lymphoblastoid cell lines provide an interleukin 1-like signal for mitogen-treated T lymphocytes via direct cell contact. J Immunol. 1985 Jun;134(6):3876-81. PMID:2985701
157. Reisman L, Suthanthiran M, Friedman J, McCrory WW. Cellular and humoral mechanisms in the pathogenesis of tubulointerstitial nephritis. Uremia Invest. 1985-1986;9(1):1-10. PMID:3915161
158. Cheigh JS, Suthanthiran M, Fotino M, Kaplan M, Evelyn M, Schechter N, Wolf CF, Riggio RR, Riehle R, Stubenbord WT, et al. Induction of donor-specific immune modulation and successful renal transplantation with a simplified method of donor-specific blood transfusion. Uremia Invest. 1985-1986;9(1):11-7. PMID:2940741
159. Suthanthiran M, Williams PS, Solomon SD, Rubin AL, Stenzel KH. Induction of cytolytic activity by anti-T3 monoclonal antibody. Activation of alloimmune memory cells and natural killer cells from normal and immunodeficient individuals. J Clin Invest. 1984 Dec;74(6):2263-71. PMID:6392343
160. Suthanthiran M, Evelyn M, Rubin AL, Stenzel KH. A reappraisal of the effects of monoclonal antibodies directed at T cell differentiation antigens. Transplantation. 1984 Dec;38(6):720-6. PMID:6239416
161. Cheigh JS, Suthanthiran M, Kaplan M, Evelyn M, Riggio RR, Fotino M, Schechter N, Wolf CF, Stubenbord WT, Stenzel KH, et al. Induction of immune alterations and successful renal transplantation with a simplified method of donor-specific blood transfusion. Transplantation. 1984 Nov;38(5):501-6. PMID:6238460
162. Suthanthiran M, Solomon SD, Williams PS, Rubin AL, Novogrodsky A, Stenzel KH. Hydroxyl radical scavengers inhibit human natural killer cell activity. Nature. 1984 Jan 19-25;307(5948):276-8. PMID:6694728
163. Riggio RR, Haschemeyer R, Cheigh J, Suthanthiran M, Stubenbord W, Tapia L, Stenzel KH. Evolution of immunosuppressive treatment modalities for renal transplant recipients. Uremia Invest. 1984-1985;8(3-4):251-5. PMID:6400155
164. Suthanthiran M, Riggio RR, Cheigh JS, Walle A, Fotino M, Stenzel KH. Presumed assault or accommodative reactions involved in human renal transplantation. Uremia Invest. 1984-1985;8(3-4):245-9. PMID:6400154
165. Novogrodsky A, Suthanthiran M, Stenzel KH. Activation of T cells via cell-cell interaction: role of growth factors and accessory cells. Uremia Invest. 1984-1985;8(3-4):175-8. PMID:6336242
166. Suthanthiran M, Garovoy MR. Immunologic monitoring of the renal transplant recipient. Urol Clin North Am. 1983 May;10(2):315-25. Review. PMID:6222530
167. Kaldany A, George K, Suthanthiran M, Catto GR, Strom TB, Carpenter CB. Long-term renal allograft survival in rats preimmunized with donor strain RT1.B antigens. Transplantation. 1983 Apr;35(4):289-93. PMID:6220493
168. Gordon BR, Suthanthiran M, Saal SD, Stenzel KH, Rubin AL. Plasmapheresis in a patient with angioimmunoblastic lymphadenopathy. Improvement in clinical and immunologic abnormalities. Cancer. 1983 Mar 1;51(5):829-33. PMID:6821848
169. Taufield PA, Suthanthiran M, Ales K, Druzin M, Resnick LM, Laragh JH, Stenzel KH, Rubin AL. Maternal-fetal immunity: presence of specific cellular hyporesponsiveness and humoral suppressor activity in normal pregnancy and their absence in preeclampsia. Clin Exp Hypertens B. 1983;2(1):123-31. PMID:6223727
170. Cheigh JS, Saal SD, Suthanthiran M, Riggio RR, Fotino M, Stubenbord WT, Stenzel KH, Rubin AL. Natural history of cadaveric kidney transplants in the absence of early acute rejection. Nephron. 1983;35(1):6-10. PMID:6193438
171. Barth RH, Cheigh JS, Sullivan JF, Chami J, Suthanthiran M, Stubenbord WT, Stenzel KH, Rubin AL. The advantage of measurement of intact PTH in the prediction of clinical response and calcium metabolism after subtotal parathyroidectomy for renal osteodystrophy. Trans Am Soc Artif Intern Organs. 1983;29:124-8. PMID:6673220
172. Suthanthiran M, Rubin AL, Novogrodsky A, Stenzel KH. Abrogation of proliferation and generation of cytotoxic T cells in human mixed lymphocyte culture reactions by modification of the cell surface with mitogenic oxidizing agents. Transplantation. 1982 Oct;34(4):209-14. PMID:6293126
173. Riggio RR, Suthanthiran M, Cheigh JS, Haschemeyer RH, Fotino MA, Stubenbord WT, Stenzel KH, Rubin AL. Enhanced kidney graft survival with retroplacental source gamma-globulin. Results of a 5-year prospective study at a single center. Transplantation. 1982 Jun;33(6):636-41. PMID:6179273
174. Suthanthiran M, Rubin AL, Novogrodsky A, Stenzel KH. Immunosuppressive properties of polar organic compounds that induce cellular differentiation in Friend erythroleukemia cells. Transplantation. 1982 May;33(5):534-40. PMID:7046164
175. Fotino M, Suthanthiran M. Role of HLA DR in renal transplantation. N Y State J Med. 1982 Mar;82(3):327-32. PMID:7045739
176. Ercolani L, Novogrodsky A, Suthanthiran M, Rubin AL, Stenzel KH. Expression of Fc mu receptors by human T lymphocytes: effects of enzymes, metabolic inhibitors, and X-irradiation. J Immunol. 1981 Nov;127(5):2044-51. PMID:6795266
177. Suthanthiran M, Rubin AL, Fotino M, Novogrodsky A, Stenzel KH. Detection of alloimmune memory cells by chemical modification of the cell surface with mitogenic oxidizing agents. Transplant Proc. 1981 Sep;13(3):1536-8. PMID:7029809
178. Cheigh JS, Fotino M, Stubenbord WT, Suthanthiran M, Riggio RR, Saal SD. Declining transplantability of prospective kidney transplant recipients. JAMA. 1981 Jul 10;246(2):135-9. PMID:7017178
179. Suthanthiran M, Rubin AL, Novogrodsky A, Stenzel KH. Biological effects of activation of human peripheral blood mononuclear cells by mitogenic oxidizing agents. I Alloantigen-independent activation of alloimmune memory cells. Cell Immunol. 1981 Mar 15;59(1):26-41. PMID:6260389
180. Suthanthiran M, Won OS, Rubin AL, Novogrodsky A, Stenzel KH. Alloantigen-independent activation of alloimmune memory cells by soluble factors from mitogen-primed cells. Transplant Proc. 1981 Mar;13(1 Pt 2):1150-2. PMID:6455819
181. Saal SD, Gordon B, Evans E, Stack J, Suthanthiran M. Plasmapheresis in the prevention and treatment of rapidly progressive renal disease. Clin Exp Dial Apheresis. 1981;5(1-2):65-78. Review. PMID:7037248
182. Suthanthiran M, Rubin AL, Novogrodsky A, Stenzel KH. Detection of alloimmune memory cells by chemical modification of the cell surface with mitogenic oxidizing agents. Transplantation. 1980 Oct;30(4):269-74. PMID:6255637
183. Riggio RR, Cheigh JS, Stenzel KH, Suthanthiran M, Chami J, Saal SD, Sullivan JF, Haschemeyer R, Tapia L, Stubenbord WT, Fotino M, DeBoccardo G, Rubin AL. Kidney transplantation; use of gamma globulin as an immunosuppressive agent. N Y State J Med. 1980 Sep;80(10):1561-3. PMID:6158719
184. Gailiunas P Jr, Suthanthiran M, Busch GJ, Carpenter CB, Garovoy MR. Role of humoral presenitization in human renal transplant rejection. Kidney Int. 1980 May;17(5):638-46. PMID:6995691
185. Kaldany A, Carpenter CB, Shadur CA, George K, Lundin AP 3rd, Suthanthiran M, Strom TB. Immunological properties of subcellular rat lymphocyte preparations. Primary allogeneic stimulation in vitro by fractions containing Ia (RT1-B), but not RT1-A antigens. J Exp Med. 1980 Apr 1;151(4):910-24. PMID:6445396
186. Suthanthiran M, Stenzel KH, Rubin AL, Novogrodsky A. Augmentation of proliferation and generation of specific cytotoxic cells in human mixed lymphocyte culture reactions by colchicine. Cell Immunol. 1980 Mar 15;50(2):379-91. PMID:6444547
187. Novogrodsky A, Suthanthiran M, Saltz B, Newman D, Rubin AL, Stenzel KH. Generation of a lymphocyte growth factor by treatment of human cells with neuraminidase and galactose oxidase. J Exp Med. 1980 Mar 1;151(3):755-60. PMID:7359085
188. Suthanthiran M, Rubin AL, Novogrodsky A, Stenzel KH. Activation of alloimmune memory cells by soluble factors: a model for elicitation of specific allograft responses by immunologically nonspecific signals. Proc Clin Dial Transplant Forum. 1980;10:207-10. PMID:6287451
189. Suthanthiran M, Stenzel KH, Rubin AL, Novogrodsky A. Generation of specific secondary cytotoxic T cells by treatment of long-term primary MLC cells with sodium periodate. Transplant Proc. 1979 Dec;11(4):1990-1. PMID:231337
190. Montoliu J, Cheigh JS, Mouradian JA, Suthanthiran M, Riggio RR, Rubin AL, Stenzel KH. Delayed hyperacute rejection in recipients of kidney transplants from HLA identical sibling donors. Am J Med. 1979 Oct;67(4):590-6. PMID:386793
191. Suthanthiran M, Catto GR, Kaldany A, George K, Garovoy MR, Strom TB, Carpenter CB. Differential antibody responses to Ag-B (A region) and Ia (B region) antigens during enhancement of rat renal allografts. Transplantation. 1979 Jul;28(1):4-9. PMID:377592
192. Suthanthiran M, Fotino M, Gibofsky A, Cheigh JS, Stenzel KH, Rubin AL, Novogrodsky A. Adverse presensitization: detection by utilization of B lymphoblastoid cell panels. Transplant Proc. 1979 Jun;11(2):1263-4. PMID:382502
193. Riggio RR, Cheigh JS, Stubenbord WT, Tapia LA, Chami J, Suthanthiran M, Stenzel KH, Rubin AL. Immunosuppressive properties of placental-source gamma globulin: results of a 5-year clinical investigative study in a cadaver kidney transplant program. Transplant Proc. 1979 Jun;11(2):1424-5. PMID:89743
194. Suthanthiran M, Fotino M, Cheigh JS, Rubin AL, Novogrodsky A, Stenzel KH. Adverse presensitization to renal transplants. Detection by utilization of a D locus antigen-defined lymphoblastoid cell panel as targets in antibody-dependent cell-mediated cytotoxicity assays. Transplantation. 1979 May;27(5):333-7. PMID:373190
195. Stenzel KH, Suthanthiran M, Rubin AL, Novogrodsky A. Detection of memory cells by chemical modification of the lymphocyte cell surface. Proc Eur Dial Transplant Assoc. 1979;16:437-41. PMID:162003
196. Riggio RR, Cheigh JS, Suthanthiran M, Stubenbord WT, Fotino M, Haschmeyer RH, Stenzel KH, Rubin AL. Human gamma globulin enhances the survival of renal allografts. Proc Eur Dial Transplant Assoc. 1979;16:426-30. PMID:95048
197. Suthanthiran M, Lagman M, Rubin AL, Stenzel KH, Novogrodsky A. Regulation of human mixed lymphocyte culture reactions: augmentation of proliferation and generation of cytotoxic cells. Transplant Proc. 1978 Dec;10(4):923-5. PMID:153618
198. Kaldany A, Carpenter CB, Suthanthiran M, Garovoy MR, Strom TB, George K. HLA-D activity in lymphocyte subcellular fractions. Transplant Proc. 1978 Dec;10(4):785-8. PMID:153612
199. Suthanthiran M, Fotino M, Cheigh JS, Novogrodsky A, Rubin AL, Stenzel KH. D lucus antigen defined lymphoblastoid cell panel allows detection of hitherto undetected adverse presensitization. Proc Clin Dial Transplant Forum. 1978 Nov 18-20;8:199-202. PMID:386312
200. Garovoy MR, Suthanthiran M, Gailiunas P, Carpenter CB, Graves M, Busch G, Tilney NL. Anti-Ia antibody eluted from rejected human renal allografts. Transplant Proc. 1978 Sep;10(3):613-6. PMID:362645
201. Gailiunas P, Suthanthiran M, Person A, Strom TB, Carpenter CB, Garovoy MR. Posttransplant immunologic monitoring of the renal allograft recipient. Transplant Proc. 1978 Sep;10(3):609-11. PMID:362644
202. Suthanthiran M, Gailiunas P, Fagan G, Strom TB, Carpenter CB, Garovoy MR. Detection of anti-donor Ia" antibodies: a strong correlate of rejection." Transplant Proc. 1978 Sep;10(3):605-7. PMID:362643
203. Suthanthiran M, Gailiunas P, Person A, Fagan G, Strom TB, Carpenter CB, Garovoy MR. Accelerated graft loss: association with presensitization to donor B-cell (Ia) antigens. Transplant Proc. 1978 Jun;10(2):471-3. PMID:354138
204. Strom TB, Carpenter CB, Tilney NL, Suthanthiran M, Catto GR, Lundin AP, Milford EL. Intragraft immune events causing vascularized organ graft rejection. Transplant Proc. 1978 Jun;10(2):389-94. PMID:354128
205. Gailiunas P, Suthanthiran M, Person A, Carpenter CB, Garovoy MR. Immunologic monitoring in the diagnosis of renal allograft rejection. Transplant Proc. 1977 Dec;9(4):1823-5. PMID:341443
206. Suthanthiran M, Gailiunas P, St Louis G, Fagan G, Carpenter CB, Garovoy MR. Presensitization to donor B-cell (Ia") antigens is associated with early allograft failures." Transplant Proc. 1977 Dec;9(4):1807-9. PMID:341440
207. Suthanthiran M, Garovoy MR, Fagan G, Gailiunas P, Carpenter CB. Evidence for close association between B-cell Fc receptors and Ia antigens, and independence from HLA-A,B locus-determined antigens. Transplant Proc. 1977 Dec;9(4):1705-7. PMID:304618
208. Gailiunas P, Person A, Suthanthiran M, Carpenter CB, Garovoy MR. Pretransplant assays of alloimmunity in predicting renal graft outcome. Proc Clin Dial Transplant Forum. 1977;7:1-3. PMID:356029
