Eric J. Mallack, M.D.
Pediatric Neurology
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Eric J. Mallack, M.D.

Pediatric Neurology

Profile Photo of Eric J. Mallack, M.D.
Accepts New Patients
Gender: Male
Language: English


Personal Statement

My goal is to provide the most comprehensive care available to children affected by neurogenetic disorders, with a special focus on the leukodystrophies. I believe in a multidisciplinary approach to care, which is a team effort between the patient, physicians, parents, social workers, nutritionists, and mental health professionals as necessary.  We aim to connect patients and families with patient advocacy groups and research opportunities to make accurate diagnoses, strengthen disease-specific support networks, and to make inroads towards treatments for the often devastating neurological diseases of childhood. 


Specialties and Expertise


  • Pediatric Neurology
  • Child Neurology


  • Leukodystrophy
  • X Linked Adrenoleukodystrophy
  • Neurogenetics
  • Hypotonia
  • Neurodevelopmental Disorder
  • Leukoencephalopathy
  • Metachromatic Leukodystrophy
  • Aicardi Goutieres Syndrome


Biography: Eric Mallack, MD, MBE is an Assistant Professor of Pediatrics and Neurology at Weill Cornell Medical College, Assistant Attending at NewYork-Presbyterian Hospital, and Assistant Attending Neurologist at Memorial Sloan Kettering Cancer Center.  He is the Director of the Leukodystrophy Center at Weill Cornell Medicine, and Neurologist in the WCM-MSKCC Metabolic Cell and Gene Therapy Program.  

Dr. Mallack completed his A.B. in Philosophy and Biomathematics at The University of Scranton.  He then simultaneously earned his Medical Doctorate from the Temple University School of Medicine, and his Master’s Degree in Bioethics (MBE) from the University of Pennsylvania School of Medicine.  Dr. Mallack completed his Pediatrics and Child Neurology Residency training at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.  He completed his post-doctoral research training under the NIH/NINDS Neurological Sciences Academic Development Award (NSADA K12) at the Massachusetts General Hospital Center for Rare Neurological Diseases.  Dr. Mallack’s clinical interests include the class of diseases known as the leukodystrophies with a special interest in X-Linked Adrenoleukodystrophy, and childhood neurogenetic disorders.  His research interests include gene therapy for the leukodystrophies and advanced neuroimaging.

About Dr. Mallack's Research Program: Dr. Mallack's translational research program allies with the Newborn Screening Program and Patient/Parent Advocacy Groups to identify presymptomatic patients with X-Linked Adrenoleukodystrophy.  He is investigating the ability of multiple advanced neuroimaging techniques, including diffusion tensor imaging, to identify patients appropriate for stem cell transplant or gene therapy prior to symptom onset.  

Dr. Mallack is an investigator on multiple gene therapy clinical trials:

Krabbe Disease: Study of Safety, Tolerability and Efficacy of PBKR03 in Pediatric Subjects With Early Infantile Krabbe Disease (GALax-C)

Canavan Disease: A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire) 

Mucopolysaccharidosis Type IIIA (“Sanfilippo Syndrome A”): Study of AAVrh10-h.SGSH Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)

Dr. Mallack is a faculty neurologist in the Center for Neurogenetics which focuses on understanding the genetic mechanisms responsible for abnormal brain development.  He is also investigating genotype-phenotype correlations in autism under the Weill Cornell Autism Research Project (WCARP).


Honors and Awards

Honors and Awards

NIH/NINDS K23 Career Development Award (2021 - 2026)

Neurological Sciences Academic Development Award, NIH-NINDS K12 Physician Scientist Award Program (2017 – 2020)

Chief Resident, Child Neurology, NY-Presbyterian Hospital/Weill Cornell Medical Center (2016 – 2017)

Bioethics and Humanity Award, Temple University School of Medicine Center for Bioethics, Urban Health, and Policy (2012)

American Academy of Neurology Medical Student Prize for Excellence in Neurology (2012)

Charles Schnall Academic Leadership Scholarship Award, Temple University School of Medicine (2011)

Arrupe Academic Scholarship, The University of Scranton (2004 – 2008)

Eagle Scout, Boy Scouts of America (2001)



Board Certifications

  • American Board of Psychiatry & Neurology (Child Neurology)

Clinical and Academic Positions

  • Assistant Attending Pediatrician - NewYork-Presbyterian Hospital
  • Assistant Professor of Pediatrics - Weill Cornell Medical College, Cornell University
  • Assistant Professor of Neurology - Weill Cornell Medical College, Cornell University

Education and Training

  • M.BE., University of Pennsylvania School of Medicine, 2012
  • M.D., Temple University School of Medicine, 2012
  • A.B., University of Scranton, 2008


Insurance Plans Accepted

The following represents most of the managed care plans accepted by this doctor. If your insurance carrier does not appear here please contact the doctor’s office as they may have individual contracts not included on this site.

* indicates this doctor is no longer accepting new patients with this insurance plan.

  • Aetna Weill Cornell Employee Managed Care Plan
  • Aetna Weill Cornell Employee PPO Plan
  • Aetna-NYP - EPO/POS
  • Affinity Access
  • Affinity Health Plan
  • Amida Care
  • Emblem Select Care
  • Empire Blue Cross/Blue Shield - Blue Access
  • Empire Blue Cross/Blue Shield - Blue Connection
  • Empire Blue Cross/Blue Shield - EPO
  • Empire Blue Cross/Blue Shield - HMO
  • Empire Blue Cross/Blue Shield - Mediblue (Senior)
  • Empire Blue Cross/Blue Shield - PPO
  • Empire Blue Cross/Blue Shield HealthPlus
  • Empire Blue Cross/Blue Shield HealthPlus - CHP
  • Fidelis Care
  • GHI - CBP
  • Health First
  • Health Insurance Plan of NY (HIP)
  • Health Insurance Plan of NY (HIP) - Medicaid
  • Medicaid
  • Medicare
  • Oxford Health Plans - Metro/Core/Charter
  • Oxford Health Plans - Liberty
  • Oxford Health Plans - Freedom
  • Rockefeller University - Trustmark
  • United Empire
  • United Healthcare
  • United Healthcare - Community Plan
  • United Healthcare Compass
  • WellCare of NY
  • WorldWide Medical

Locations and Appointments

External Relationships

External Relationships

Relationships and collaborations with for-profit and not-for profit organizations are of vital importance to our faculty because these exchanges of scientific information foster innovation. As experts in their fields, WCM physicians and scientists are sought after by many organizations to consult and educate. WCM and its faculty make this information available to the public, thus creating a transparent environment.

No External Relationships Reported