Peripheral Neuropathy is common, affecting approximately 20 million people in the United States. It causes weakness, sensory loss and pain, which in severe cases can be debilitating. It is idiopathic in approximately one third of cases, caused by diabetes in another third, and the remainder have such diverse etiologies as autoimmunity, neoplasia, infections, nutritional deficiencies, toxins, trauma, or genetic defects.
Patients with neuropathy have many medical needs. Proper diagnosis requires sophisticated electrophysiologic, radiologic, and blood testing capabilities. Therapy is both medical and supportive, and directed at alleviating the symptoms as well as treating the underlying disease. Most of these services are provided by the neurologist, whereas others require referral to other specialties. It is largely an outpatient disease, but it mostly effects and elderly population, and hospitalization is sometimes required for the underlying disease, or for neuropathic complications such as bony fractures from falls, or foot ulcerations and infections in patients with diabetes.
Clinical Trial Enrollment
We are currently enrolling subjects in the following clinical trials:
- Neuropathic Pain Associated With Diabetic Neuropathy. These studies seek individuals 18 to 75 years of age with Diabetes and Prickling, Tingling, Numbness or Pain in Feet. To be eligible, you must: 1) Be 18 years of age or older 2) Have either Type1 or Type 2 diabetes 3) Not be pregnant or intend to become pregnant during the study Study participants will be assigned to take an experimental drug or placebo (no active treatment) capsules once daily. The various studies last approximately 9 to 24 weeks. This drug has not been approved by the Food & Drug Administration (FDA). There is no cost for your participation.
- Diabetic Sensorimotor Polyneuropathy. This study seeks individuals 18 to 70 years of age with Diabetic sensorimotor polyneuropathy. Diabetic sensorimotor polyneuropathy is a nerve disorder in diabetics, and is caused by inflammation or deterioration of the nerves.To be eligible, you must: 1) Be 18 years of age or older 2) Type I or Type II, insulin dependent or non insulin dependant diabetes for at least six months prior to study entry 3) Not be pregnant or intend to become pregnant during the study Study participants will be assigned to take an experimental drug or placebo (no active treatment) tablets once daily. The various studies last approximately 52 weeks. This drug has not been approved by the Food & Drug Administration (FDA). There is no cost for your participation.
If you are interested in any of the clinical trials listed above, please call Michelle Renard, RN Research Study Coordinator Peripheral Neuropathy Center at (212) 888-8516.