Kovacs G, Fine RN, Worgall S, Schaefer F, Hunziker EB, Skottner A, Mehls O. Growth hormone prevents steroid-induced growth depression in health and uremia. Kidney Int, 1991; 40:1032-40
Kovacs G, Fine RN, Worgall S, Schaefer F, Hunziker EB, Mehls O. Recombinant growth hormone overcomes the growth suppressive effect of methylprednisoe in uremic rats. Ped Nephrol, 1991; 4:552-6
Ritz E, Toenshoff B, Worgall S, Kovacs G, Mehls O. Influence of growth hormone and insulin-like growth factor-1 on kidney function and kidney growth. Pediatr Nephrol 1991;4:509-12
Worgall S, Feth F, Kleschin S, Manz F, Rascher W. Endothelin-1 excretion is related to urinary flow. Clin Nephrol 1994;41:331-7
Tamas P, Worgall S, Sulyok E, Rascher W. Renal electrolyte and water handling in normal pregnancy: possible role of endothelin-1. Eur J Obst Gynaecol 1994;55:89-95
Sulyok E, Adamovich K, Worgall S, Rascher W. Urinary endothelin-1 excretion in furosemide-treated human neonates. Acta Paediatr Hung 1994;34:51-60
Kiess W, Worgall S, Rascher W. Aetiopathogenesis of type I diabetes. Monatsschr Kinderheilkd 1995;143:S2-11
Worgall S, Kiess W, Rascher W. Diabetes mellitus-Application of an antihypertensive therapy. Monatsschr Kinderheilkd 1995;144:102-9
Worgall S, Haenze J, Wagner R, Peiser C, Lang RE, Sulyok E, Rascher W. Characterization of ouabain-like immunoreactivity in human urine. J Hypertension 1996;14:623-8
Haenze J, Christiansen H, Schueler D, Worgall S, Lampert S, Rascher W. Gene expression of neuropeptide Y and neuropeptide Y1 receptor in relation to protooncogene tyrosine kinase A, nerve growth factor low affinity receptor and transcription factor N-myc in human neuroblastomas. Int J Oncology 1996;3:1182-7
Worgall S, Haenze J, Wagner R, Peiser C, Lang RE, Sulyok E, Rascher W. Characterization of ouabain-like immunoreactivity in human urine. J Hypertension 1996;14:623-8
Sulyok E, Adamovits K, Worgall S, Rascher W. Urinary excretion of endogenous ouabain-like substance in furosemide-treated neonates: its relation to renal excretory pattern and endocrine factors. Biol Neonate 1997; 72:352-62
Worgall S, Rascher W, Gyodi G, Nyul Z, Baranyai Z, Sulyok E. Urinary excretion of endogenous ouabain-like substance is reduced in NaCl supplemented premature infants. Biol Neonate. 1997; 72: 337-44
Hanze J, Worgall S, Rascher W. Monitoring of antisense effects of oligonucleotides targeted to the neuropeptide Y Y1 receptor gene. Eur J Pharmacol. 1997; 330:87-92
Wolff G, Worgall S, Van Rooijen N, Song Wen-ru, Harvey B-G, Crystal RG. Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. J Virol 1997; 71:624-9
Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Innate immune mechanisms dominate elimination of adenovirus vectors following in vivo administration. Hum Gene Ther 1997; 8:37-44
Worgall S, Leopold PL, Wolff G, van Roijen N, Crystal RG. Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract. Hum Gene Ther 1997; 8:1675-84
Leopold PL, Ferris B, Grinberg I, Worgall S, Hackett NR, Crystal RG. Fluorescent Virions: Dynamic Tracking of the Pathway of Adenovirus Gene Transfer Vectors in Living Cells. Hum Gene Ther 1998; 9: 367-78
Topf N, Worgall S, Hackett NR, Crystal RG. Regional #147;Pro-Drug#148; Gene Therapy: Intravenous Administration of an Adenoviral Vector Expressing the E.coli Cytosine Deaminase Gene and Systemic Administration of 5-Fluorocytosine Suppresses Growth of Hepatic Metastasis of Colon Carcinoma. Gene Ther 1998; 5: 507-13
Kaner RJ, Worgall S, Leopold PL, Stolze E, Milano E, Hidaka C, Ramalingam R, Hackett NR, Singh R, Bergelson J, Finberg R, Falck-Pedersen E, Crystal RG. Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie /adenovirus receptor. Am J Respir Cell Mol Biol 1999; 20: 361-70
Worgall S, Singh R, Leopold PL, Kaner RJ, Hackett NR, Topf N, Moore MAS, Crystal RG. Selective expansion of alveolar macrophages in vivo by ex vivo adenovirus-mediated transfer of the murine granulocyte-macrophage colony stimulating factor cDNA to and transplantation of modified macrophages to the lungs of syngeneic mice. Blood 1999; 93: 655-66
Ramalingam R, Rafii S, Worgall S, Crystal RG. E1-E4 Adenoviral gene transfer vectors function as a #147;pro-life#148; signal to promote survival of primary human endothelial cells. Blood 1999; 93: 2936-44
Worgall S, Connor R, Kaner RJ, Fenamore E, Sheridan K, Singh R, Crystal RG. Expression and use of HIV-1 coreceptors by human alveolar macrophages. J Virol 1999; 73: 5865-74
Kovacs GT, Worgall S, Schwalbach P, Steichele T, Mehls O, Rosivall Hypoglycemic effects of insulin-like growth factor-1 in experimental uremia: can concomitant growth hormone administration prevent this effect? Horm Res 1999;51:193-200
Miyazawa N, Leopold PL, Hackett NR, Ferris B, Worgall S, Falck-Pedersen E, Crystal RG. #147;Fiber swap#148; between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors. J Virol 1999; 73:6056-65
Bezdicek P, Worgall S, Kovesdi I, Kim M-K, Park J-G, Vincent T, Leopold PL, Schreiber AD, Crystal RG. Enhanced liver uptake of opsonized red blood cells following in vivo transfer of Fc(RII cDNA. Blood 1999;10:3448-55
Worgall S, Bezdicek P, Kim M-K, Park J-G, Prince A, Kovesdi I, Schreiber AD, Crystal RG. Augmentation of pulmonary host defense against Pseudomonas by Fc(RIIA cDNA transfer to the respiratory epithelium. J Clin Invest 1999; 104:409-18
Harvey B-G, Worgall S, Ely S, Leopold PL, Crystal RG. Cellular immune responses of healthy individuals to intradermal administration of an E1GE3G adenovirus gene transfer vector. Hum Gene Ther 1999; 10: 2823-37
Ramalingam R, Rafii S, Worgall S, Hackett NR, Crystal RG. Induction of endogenous genes following infection of human endothelial cells with an E1GE4 adenovirus gene transfer vector. J Virol 1999; 73: 10183-90
Worgall S, Worgall TS, Singh R, Leopold PL, Hackett NR, Crystal RG. Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells. Mol Ther 2000; 1: 39-48
Ramalingam R, Worgall S, Rafii S, Crystal RG. Downregulation of CXCR4 gene expression in primary human endothelial cells following infection with E1(-)E4( ) adenovirus gene transfer vectors. Mol Ther 2000; 4: 381-6
Kikuchi T, Worgall S, Singh R, Moore MA, Crystal RG. Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4 T cells. Nat Med 2000; 10:1154-9
Rafii S, Dias S, Meeus S, Hattori K, Ramachandran R, Feuerback F, Worgall S, Hackett NR, Crystal RG. Infection of endothelium with E1(-)E4( ), but not E1(-)E4(-), adenovirus gene transfer vectors enhances leukocyte adhesion and migration by modulation of ICAM-1, VCAM-1, CD34, and chemokine expression. Circ Res 2001; 88:903-10
Worgall S, Kikuchi T, Singh R, Martushova K, Lande L, Crystal RG. Protection against pulmonary infection with Pseudomonas aeruginosa following immunization with P. aeruginosa-pulsed dendritic cells. Infect Immun 2001; 69:4521-7
Seidman MA, Hogan SM, Wendland RL, Worgall S, Crystal RG, Leopold PL. Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle. Mol Ther 2001; 4:13-21
Worgall S, Martushova K, Busch A, Lande L, Crystal RG. Apoptosis induced by Pseudomonas
aeruginosa in antigen presenting cells is diminished by genetic modification with CD40 ligand.
Ped Res 2002; 52: 636-44
Palma M, Worgall S, Quadri LE. Transcriptome analysis of the Pseudomonas aeruginosa response to iron. Arch Microbiol 2003; 180:374-9
Palma M, DeLuca D, Worgall S, Quadri LE. Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide. J Bacteriol 2004; 186: 248-52
Worgall S, Busch A, Rivara M, Bonnyay D, Leopold P, Hackett N, Rovelink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG. Adenovirus-vector modifications to increase infection of dendritic cells enhances transgene-specific cellular immune responses. J Virol 2004 78: 2572-80
Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D, Dinner M, Wisniewski K, Kaplitt M, Greenwald BM, Howell JD, Strybing K, Dyke J, Voss H. Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis. Hum Gene Ther 2004; 15: 1131-54
Worgall S. A realistic chance for gene therapy in the near future. Pediatr Nephrol 2005; 20: 118-24
Palma M, Zurita J, Ferreras JA, Worgall S, Shi L, Campagne F, LEN Quadri. Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-1dependent regulation of the bacterial oxidative stress adaptive response. Infect Immun 2005; 73: 2958-66
Worgall S, Krause A, Rivara M, Hee KK, Vintayen EV, Hackett NR, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG. Protection against pulmonary infection with P. aeruginosa following immunization with a replication deficient adenovirus modified to contain a P. aeruginosa OprF epitope in the adenovirus capsid. J Clin Invest 2005; 115: 1281-9
Worgall S, Heguy A, Luettich K, Harvey BG, Quadri LE, Crystal RG. Similarity of Patterns in Gene Expression of Human Alveolar Macrophages Evoked by Pseudomonas aeruginosa and Burkholderia cepacia. Infect Immun 2005; 73: 5262-8
Arkin LM, Sondhi D, Worgall S, Suh LH, Hackett NR, Kaminsky SM, Hosain SA, Souweidane MM, Kaplitt MG, Dyke JP, Heier LA, Ballon DJ, Shungu DC, Wisniewski KE, Greenwald BM, Hollmann C, Crystal RG. Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders. Hum Gene Ther 2005;16:1028-36
Heguy A, O'Connor TP, Luettich K, Worgall S, Cieciuch AA, Harvey B-G, Hackett NR, Crystal RG. Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and non-smokers reveals a previously unrecognized subset of genes modulated by cigarette smoking. J Mol Med 2006; 84: 318-28
Krause A, Joh J H, Hackett NR, Roelvink PW, Bruder JT, Wickham TJ, Kovesdi I, Crystal RG, Worgall S. Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity. J Virol 2006; 80: 5523-30
Kobayashi H, Worgall S, Crystal RG. Interaction of P. carinii with dendritic cells and resulting host responses to P. carinii. J Immunother 2007; 30: 54-63
Dyke JP, Voss HU, Sondhi D, Hackett NR, Worgall S, Heier LA, Kosofsky BE, Ulug AM, Shungu DC, Mao X, Crystal RG, Ballon D.Assessing Disease Severity in Late Infantile Neuronal ceroid lipofuscinosis using quantitative MR diffusion-weighted imaging. AJNR Am J Neuroradiol. 2007, 28: 1232-6
Worgall S, Kekatpure MV, Heier L, Ballon D, Dyke JP, Shungu D, Mao X, Kosofsky B, Kaplitt MG, Souweidane MM, Sondhi D, Hackett NR, Hollmann C, Crystal RG. Neurological deterioration in late infantile neuronal ceroid lipofuscinosis. Neurology. 2007; 69: 521-35
Saitoh, H, Heguy A, Leopold PL, Harvey BG, O'Connor TP, Worgall S, Hackett NR, Crystal, RG. Role of alveolar macrophage-derived expression of ADAM10 in the pathogenesis of emphysema associated with cigarette smoking. Clin Trans Sci 2009; 2:50-56
Xu Y, Tertilt C, Krause A, Quadri LN, Crystal RG, Worgall, S. Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells. Respiratory Research 2009, 10:26
Tertilt C, Joh J, Krause A, Chou P, Schneeweiss K, Crystal RG, Worgall S. Expression of B cell activiating factor enhances protective immunity of a vaccine against P. aeruginosa. Infect Immun 2009; 77:3045-3055
Krause A, Xu Y, Joh J, Hubner R, Gess A, Ilic T, Worgall S. Overexpression of sonic hedgehog in the lung mimics the effect of lung injury and compensatory lung growth on pulmonary Sca-1 and CD34 positive cells. Mol Ther 2009; 18: 404-412
Xu Y, Krause A, Hamai H, Harvey BG, Worgall TS, Worgall S. Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA. PLoS One. 2010 Jun 8;5(6):e11004
Shiratsuchi T, Rai U, Krause A, Worgall S, Tsuji M. Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice. J Clin Invest 2010; 10.1172
