Kevin Holcomb, M.D.
Gynecologic Oncology
Publications
Seto-Young D, Avtanski D, Strizhevsky M, Parikh G, Patel P, Kaplun J, Holcomb K, Rosenwaks Z, Poretsky L. Interactions among peroxisome proliferator activated receptor-gamma, insulin signaling pathways, and steroidogenic acute regulatory protein in human ovarian cells. J Clin Endocrinol Metab 92(6): 2232-9.
Dos Santos LA, Slomovitz BM, Huang,M, Holcomb K, Ramirez PT, Caputo TA. Palliative laparoscopic end colostomy in a nonagenarian. JSLS 2008 Oct-Dec;12(4):410-13.
Huang M, Musa F, Holcomb K. Posterative small bowel herniation through a 5mm non-bladed laparoscopic trocar site. JSLS 2010 Apr-Jun;14(2):289-91.
Huang M, Chadha MD, Musa F, Friedmann P, Kolev V, Holcomb K. Lymph nodes: is total number or station number a better predictor of lymph node metastasis in endometrial cancer? Gynecol Oncol. 2010 Nov;119(2):295-8
Adams BN, Brandt JS, Loukeris K, Holcomb K. Embryonal rhabdomyosarcoma of the cervix and appendiceal carcinoid tumor in a 43 year old woman. Obstet Gynecol. 2011 Feb;117(2 Pt 2):482-4.
Frey MK, Inhow SB, Heyman KP, Slomovitz BM, Kessler R, Worely MJ, Holcomb K. Minimally invasive staging of endometrial cancer is feasible and safe in elderly women. J Minim Invasive Gynecol. 2011 Mar-Apr;18(2):200-4.
Adams BN, Musa FB, Taylor J, Holcomb K. AlloDerm Graft Mimmicking Uterine Carcinosarcoma Recurrence on PET/CT. Submitted for publication. Gynecol Oncol 2011.
Holcomb K, Vucetic Z, Miller MC, Knapp RC. HE4 Offers Superior Specificity in the Differentiation of Benign and Malignant Masses in Premenopausal Women. Am J Obstet Gynecol. 2011. Oct;205(4)358.e1-358.e6.
Musa F, Adams B, Holcomb K, Pirog E. Mucinous adenocarcinoma of the endometrium confers increased risk of lymph node metastases. Submitted Gynecol Oncol 2011
Damario MA, Holcomb K, Bodack MP. Bilateral femoral neuropathy complicating a combined laparoscopic-vaginal procedure. J Am Assoc Gynecol Laparosc, 1996 Nov,4:1,69-72
Abulafia O, Sclafani S, Holcomb K, Gates EJ, Sherer D. Percutaneous transluminal endovascular graft placement for massive hemorrhage due to recurrent cervical cancer associated erosion of the external iliac artery. Amer J Obstet Gynecol . 1998 Mar; 178(3):618-620
Holcomb K, Maiman M, Dimaio T, Gates EJ. Rapid progression to invasive cervix cancer in a woman infected with the human immunodeficiency virus. Obstet Gynecol 1998 May; 91(5 pt. 2):848-850
Abulafia O, Cohen HL, Zinn DL, Holcomb K, Sherer D. Application of transvaginal ultrasound for the diagnosis of vesico-vaginal fistula. J Ultrasound Med 1998 (17); 333-335
Fruchter R, Maiman M, Arrastia CD, Matthews R, Gates EJ, Holcomb K. Is HIV Infection a Risk Factor for Advanced Cervical Cancer? J Acquir Immune Defic Syndr Hum Retrovirol 1998 Jul 1;18(3):241-245
Holcomb K, Abulafia O, Matthews RP, Gabbur N, Lee YC, Buhl A. The effect of pretreatment staging laparotomy on survival in locally advanced cervical carcinoma. Eur J Gynecol Oncol 1999;20(2):90-93
Holcomb K, Abulafia O, Montalto N, Lee YC, Matthews RP. Multiple solid tumors in a woman exposed to the excess radiation of the Chernobyl Nuclear Power Plant disaster. Eur J Gynecol Oncol 1999;20(3):174-176
Holcomb K, Matthews RP, Abulafia O, Chapman J, Lee YC, Buhl A. The significance of ASCUS in HIV-positive women. Gynecol Oncol 1999;75:118-121
Holcomb K, Matthews RP, Abulafia O, Chapman J, Lee YC, Buhl A. The efficacy of cervical conization in the treatment of cervical intraepithelial neoplasia in HIV-positive women. Gynecol Oncol 1999;74:428-431
Abulafia O, Ruiz J, Holcomb K, Dimaio T, Matthews R, Lee YC. Angiogenesis in Stage I invasive and low malignant potential epithelial ovarian carcinoma. Obstet Gynecol 2000 Apr 1;95(4):548-552.
Holcomb K, Francis M, Ruiz J, Abulafia O, Matthews R. Pleomorphic rhabdomyosarcoma of the uterus in a postmenopausal woman with elevated serum CA125. Gynecol Oncol 1999;74:499-501
Lee Y, Abulafia O, Montalto N, Holcomb K, Matthews R, Golub R. Malignant transformation of an ovarian mature cystic teratoma presenting as a rectal mass. Gynecol Oncol 1999;75(3):499-503
Lee YC, Min D, Holcomb K, Buhl A, DiMaio T, Abulafia O. Computed tomography guided core needle biopsy diagnosis of pelvic actinomycosis. Gynecol Oncol 2000; 79(2):318-323
Lee YC, Holcomb K, Buhl A, Holden J, Abulafia O. Rapid progression of primary vaginal squamous cell carcinoma in a young HIV infected woman. Gynecol Oncol 2000;78:380-382
Abulafia O, Matthews RP, Holcomb K, Buhl A, Lee YC. Magnetic resonance imaging in the preoperative determination of tumor resectability in previously irradiated groin tumor. Gynecol Obstet Invest 2001;51(2):143-4.
Holcomb K, DiMaio TM, Nicastri AD, Matthews RP, Lee YC, Buhl A. Cone biopsy and pathologic findings at radical hysterectomy in stage I cervical carcinoma. Obstet Gynecol 2001 Nov;98(5 Pt 1):779-82
Holcomb K, Gabbur N, Tucker T, Matthews R, Lee Y, Abulafia O. 60Cobalt versus linear accelerator in the treatment of locally advanced cervix carcinoma: A comparison of survival and recurrence patterns. Eur J Gynaecol Oncol. 2001;22(1):16-9.
Buhl A, Landow S, Lee YC, Holcomb K, Heilman E, Abulafia O. Microcystic adnexal carcinoma of the vulva. Gynecol Oncol 2001 Sep;82(3):571-574
Holcomb K., Delatorre R, Pedemonte B, McLeod C, Anderson L, Chambers JT. E-cadherin expression in endometrioid, papillary serous, and clear cell carcinoma of the endometrium. Obstet Gynecol 2002 Dec;100(6):1290-95.
Holcomb K, Runowicz CD. Cancer Screening. Postgraduate Obstetrics and Gynecology. 2003 Mar;23(5):1-7
Seto-Young D, Leonardi O, Holcomb K, Park A, Salehi M, Chang P, Yih M, Rosenwaks Z, Poretsky L. Hormonally active non-transformed human ovarian cell culture from oophorectomy specimens: methods of development and characterization. Horm Res. 2005;64(5):238-47
Seto-Young D, Paliou M, Schlosser J, Avtanski D, Park A, Holcomb K, Chang P, Poretsky L.Thiazolidinedione action in the human ovary: direct effects on steroidogenesis and insulin-like growth factor binding protein-1 (IGFBP-1) production. J Clin Endocrinol Metab. 2005 Nov;90(11):6099-105
ABSTRACTS
Huang M, Musa F, Friedmann P, Kolev V, Chadha M, Holcomb K. Lymph node count does not accurately predict lymph node metastasis in endometrial cancer. Gynecol Oncol 2010; 116(3 supplement 1):S63
Huang M, Musa F, Friedmann P, Kolev V, Chadha M, Holcomb K. The impact of lymph node count and the number of nodal stations sampled on survival in endometrial cancer. Gynecol Oncol 2010; 116(3 supplement 1):S71
Holcomb K, Vucetic Z, Miller C, Knapp RC. Human Epididymis protein 4 Increases Specificity for the Detection of Invasive Epithelial Ovarian Cancer in Premenopausal Women Presenting with an Adnexal Mass. Gynecol Oncol 2011; 120: S69-70.
Musa F, Adams B, Holcomb K, Pirog E. Mucinous adenocarcinoma of the endometrium confers increased risk of lymph node metastases. Mod Pathol 2011;24: 233A-273A, Abstract 1107
Holcomb K, Caputo T, Curtin J, Venkatraman E, Hoskins W. Stromal cell tumors of the ovary: A clinicopathologic review of 51 cases from 1976-1994. Proc Annu Meet Am Soc Clin Oncol 1996;15:A833
Holcomb K, Matthews RP, Abulafia O, Chapman J, Lee YC, Buhl A. The significance of ASCUS in HIV-positive women. Gynecol Oncol 1999 Mar;72(3):458
Holcomb K, Matthews RP, Abulafia O, Chapman J, Lee YC, Buhl A. The efficacy of cervical conization in the treatment of cervical intraepithelial neoplasia in HIV-positive women. Gynecol Oncol 1999 Mar;72(3):456
Holcomb K, DiMaio TM, Nicastri AD, Matthews RP, Lee YC, Buhl A, Abulafia O. Correlation between cone biopsy and radical hysterectomy findings in stage I cervical carcinoma. Gynecol Oncol 2000 Feb;76(2):246
Abulafia O, Ruiz J, Holcomb K, Dimaio T, Matthews R, Lee YC, Sherer DM. Angiogenesis in invasive and borderline epithelial ovarian carcinoma. J Soc Gynecol Invest 2000; 7(1):64A-65A
Walker T, Ayre K, Holcomb K, Matthews RP, Jean-Pierre C. The outcome of early and late stage papillary serous and clear cell endometrial cancer when compared to endometrioid carcinoma. J Assoc Acad Min Phys 2000; 11(4):71
Gonzales M, Holcomb K, Lewis-Morris V, Hedley S. Complications after cone biopsy in women infected with the Human Immunodeficiency Virus. Obstet Gynecol 2002;99(4 supplement):39S
Connell K, Holcomb K, Matthews R, Moon E. Patient and caregiver characteristics associated with refused trial of labor after cesarean delivery. Obstet Gynecol 2002;99(4 supplement):52S
Seto-Young, D, Leonardi O, Holcomb K, Kaplun J, Omry G, Park A, Levy E, Marzieh Salehi, Bravo-Vera, R, Sheikh A, Chang P, Poretsky L. 2004 Characterization of a non-transformed human ovarian cell culture: Regulation of Steroidogenesis by gonadotropins and insulin . The Endocrine Society#146;s 86th Annual Meeting in New Orleans.
Park A, Poretsky L, Holcomb K, Chang P, Seto-Young D. The effects of rosiglitazone on human ovarian steroidogenesis and IGFBP1 production in-vitro. Poster presentation, The Society of Gynecologic Investigation 2005 annual meeting.
Seto-Young D, Paliou M, Schlosser J, Patel P, Park A, Avtanski D, Latif W, Babar N, Yeshou D, Omry G, Holcomb K, Poretsky, L. Peroxisome proliferator activated receptor-γ (PPAR- γ) in human ovarian cells: its role in regulation of steroidogenesis and IGFBP-1 production. 87th Annual Meeting of the Endocrine Society, San Diego, CA, June 2005
BOOK CHAPTERS
Holcomb K, Caputo TA, Knapp RC. Diagnosis of ovarian cancer. Progress in Obstetrics and Gynecology. Chervenak F, Studd J, Tan SL (eds) 18th edition. New York, NY: Churchill Livingstone 2008
Holcomb K. Runowicz CD. Cervical Cancer Screening. Surg Oncol Clin N Am. 2005 Oct;14(4):777-797
INTERACTIVE CD-ROM
Holcomb K, Roy WT, Chambers JT. Management of abnormal Pap smears. Decker Electronic Publishing, 3:6 2003
